Yazar "Özyilmaz F." seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Detection of protein p53 in gastric carcinomas: An immunohistochemical study of 50 cases
    (2000) Özyilmaz F.; Altaner Ş.; Kutlu A.K.
    Methods: p53 protein which is a tumor supressor gen production was investigated in 50 primary gastric carcinomas by immunohistochemical study. Results: p53 immunreactivity was detected in 66 per cent (n=33) of all cases. Abnormal p53 expression were found in 17 of the 20 (85 %) intestinal carcinomas, in 13 of the 22 (59 %) diffuse carcinomas and in 3 of the 8 (37.5 %) undifferantiated gastric carcinomas. Positive staining was not seen in normal epithelium and in epithelium with intestinal metaplasia which are near to the tumoral tissue. Ratio of positive immunostaining with p53 was higher in cases older than 50 years, in intestinal type tumors and also in tumors showing expanding type pattern and without having perineural invasion. No relation was found between p53 staining and parameters such as nuclear grade, invasion depth, lymph node invasion and sex. Conclusions: The results of the present immunohistochemical study of p53 accumulation in gastric carcinomas suggest that gene alterations of p53 are not rare in gastric carcinomas and may participate in the carcinogenesis of intestinal type carcinomas of the stomach.
  • Küçük Resim Yok
    Öğe
    Fibrous dysplasia of the spine with sarcomatous transformation: a case report and review of the literature
    (Springer-Verlag, 1995) Yalniz E.; Er T.; Özyilmaz F.
    A fibrosarcoma is reported in the spine of a 53-year-old man with polyostotic fibrous dysplasia. There was no history of endocrine disturbances and no previous irradiation. Malignant transformation in fibrous dysplasia is rare. A review of the literature reveals 101 cases of malignant degeneration occurring in fibrous dysplasia. We believe that this is the first report of sarcomatous change arising in an area of fibrous dysplasia in the spine. © 1995 Springer-Verlag.
  • Küçük Resim Yok
    Öğe
    Small cell carcinoma of the rectum; Report of a case
    (2002) Tokatli F.; Koçak Z.; Özyilmaz F.; Uygun K.; Çaloglu M.; Uzal C.
    Primary small cell undifferentiated carcinoma of the colon and rectum is a relatively rare tumour with an overall incidence of less than 1% among all colorectal cancers. These tumours are highly aggressive as distant metastases occur even when the primary tumour is limited to the submucosa or mucosa. Despite the mean survival being around 6 months, long-term survival may be achieved in patients with localized disease treated with curative resection and adjuvant therapy. We report on a patient with Dukes' C small cell carcinoma (SCC) of the rectum who underwent surgery followed by pelvic irradiation and chemotherapy and achieved long-term survival.