Kiyak M.V.Yesilada A.K.Sevin K.Z.Usta U.2024-06-122024-06-1220120001-5423https://hdl.handle.net/20.500.14551/16969Malignant melanoma is an aggressive tumor of melanocytes whose primary function is producing melanin pigment. Though they vary according to the microscopical subtype, these tumors often arise in the sun-exposed skin of elderly individuals, in the acral regions and in the palms and soles of the hands and feet. A 56-year-old patient visited the emergency department of our hospital with complaints of a sudden hemorrhage from a mass on her left thigh which had appeared five months ago. On physical examination a brown-black mass with dimensions of 18 x 16 x 5 cm, protruding from the skin with a partially and actively hemorrhagic, ulcerated surface, was found on the left gluteal region. The mass was excised surgically with 3 cm safe surgical margins. Histopathologically the lesion was diagnosed as "nodular malignant melanoma - Clark level 5". A malignant melanoma of such a large size is very exceptional in the literature; thus it is presented here with its interesting rapid clinical course.eninfo:eu-repo/semantics/closedAccessHistopathology; Malignant Melanoma; SurgeryKi 67 Antigen; Article; Case Report; Female; Human; Immunohistochemistry; Lymph Node Dissection; Melanoma; Metabolism; Middle Aged; Pathology; Skin Tumor; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Lymph Node Excision; Melanoma; Middle Aged; Skin Neoplasms; Mlcs; MlownArticle54259622-s2.0-8487918944223565846Q4