Çeltik C.Turan Ç.Acipayam C.Küçüku?urluo?lu Y.Karasaliho?lu S.2024-06-122024-06-1220101300-0381https://hdl.handle.net/20.500.14551/17344The risk of fulminant liver failure due to hepatitis A infection increases in the patients with underlying chronic liver diseases and hepatotoxic drug-use. In this case report, we aimed to emphasize the development of fulminant liver failure due to hepatitis A infection and importance of hepatitis A vaccination in these cases. A five-year age boy who treated with sodium valproate for three years was admitted with the symptoms of fulminant liver failure and encephalopathy to our emergency clinic. Hepatitis A IgM-antibody was found positive and serum sodium valproate level was mildly elevated. In conclusion, fulminant progression risk due to hepatitis-A infection increase in the patients using hepatotoxic drug such as sodium valproate. Therefore, hepatitis-A vaccination for these cases is important for decreasing the risk of fulminant hepatitis. Copyright © 2010 by Türkiye Klinikleri.trinfo:eu-repo/semantics/closedAccessChild; Hepatic Encephalopathy; Hepatitis A; Hepatitis A Vaccines; Liver Failure, Acute; Valproic AcidAlanine Aminotransferase; Aspartate Aminotransferase; Carnitine; Flumazenil; Hepatitis A Antibody; Hepatitis A Vaccine; Immunoglobulin M Antibody; Lactulose; Levodopa; Penicillin G; Ranitidine; Valproic Acid; Vitamin K Group; Antibody Titer; Article; Case Report; Child; Drug Blood Level; Electroencephalogram; Emergency Ward; Febrile Convulsion; Hepatic Encephalopathy; Hepatitis A; Human; Liver Failure; Male; Preschool ChildArticle1921761792-s2.0-77953790531Q4