Öztunç F.Yüksel A.Madazli R.Gökalp S.Dericio?lu A.2024-06-122024-06-1220131300-0306https://hdl.handle.net/20.500.14551/17338Objective: To evaluate the incidence, prognosis and associated cardiac and extracardiac anomalies with fetal dextrocardia. Material and Methods: The fetal echocardiographic databases (3556 examination) of Cerrahpasa Medical Faculty Pediatric Cardiology Unit were retrospectively reviewed from 2000 to 2011. Perinatal outcome and cardiac/extracardiac anomalies associated with 39 consecutive fetuses with a fetal dextrocardia are evaluated. Results: The incidence was 1.1% (39/3556). Primary dextrocardia incidence was 0.6% (22/3556). Prenatal karyotype analysis was performed in 25 fetuses and none of them had a chromosome anomaly. Of the 37 pregnancies that perinatal outcome could be gained; 11 (29.7%) had termination of pregnancies and 16 (43.2%) had fetal or neonatal loss. Perinatal survive rate was 27.1% (10/37). Secondary dextrocardia was caused by diaphragmatic hernia in 76% of cases. Of the primary dextrocardia cases 18%, 36% and 45% of the fetuses were with situs inversus, ambiguus and solitus respectively. Structural cardiac malformations were found in 25%, 100% and 80% of situs inversus, ambiguus and solitus fetuses respectively. Most of the cardiac malformations were complex cardiac anomalies. Conclusion: Fetal dextrocardia is associated with complex cardiac malformations and high perinatal mortality. Pregnancies with fetal dextrocardia should be managed together with a perinatolog and a pediatric cardiologist in a team approach. Copyright © 2013 by Tükiye Klinikleri.trinfo:eu-repo/semantics/closedAccessColor; Dextrocardia; Doppler; Echocardiography; Pregnancy OutcomeArticle; Chromosome Aberration; Congenital Disorder; Dextrocardia; Diaphragm Hernia; Female; Fetus; Fetus Wastage; Heart Disease; Human; Incidence; Karyotyping; Outcome Assessment; Perinatal Mortality; Pregnancy Termination; Prenatal Diagnosis; Prognosis; Retrospective Study; Situs Ambiguus Viscerum; Situs Inversus; Situs Solitus; Survival RateArticle2342202242-s2.0-84890399491N/A