Ucar, Fatih Mehmet2024-06-122024-06-1220161471-2261https://doi.org/10.1186/s12872-016-0367-3https://hdl.handle.net/20.500.14551/22793Background: Oxidation and inflammation play significant roles in the pathogenesis of coronary artery diseases. Monocyte count to high-density lipoprotein (HDL) cholesterol ratio (MHR) is a new marker and has revealed as an indicator of inflammation in the literature. The present study aimed to search the effect of MHR on in-stent restenosis (ISR) in patients with stable or unstable angina pectoris undergoing bare-metal stent (BMS) implantation. Methods: A total of 468 consecutive stable or unstable angina pectoris patients (mean age 60.3 +/- 10.1 and 70 % men) who had undergone successful BMS implantation were included the study. Serum samples were obtained before the procedure. Results: The mean period between two coronary angiography procedures was 14 +/- 7.9 months. The baseline MHR levels were significantly higher in patients that had ISR (odds ratio, 3.64; 95 % confidence interval, 2.45-4.84; P < 0. 001). Stent diameter, the time between the two coronary angiographic studies, uric acid and MHR levels emerged as independent predictors of ISR. Conclusions: Our results indicate that elevated MHR is an independent and powerful predictor of ISR in patients with stable or unstable angina pectoris who underwent successful BMS implantation.en10.1186/s12872-016-0367-3info:eu-repo/semantics/openAccessNovel MarkerMonocyte /HDL Cholesterol RatioInstent RestenosisBare MetalPercutaneous Coronary InterventionDensity-LipoproteinIntimal HyperplasiaArtery-DiseaseHeart-DiseaseInflammationAngioplastyThrombosisEraArticle16Q3WOS:0003857744000012-s2.0-8498931150527716070Q2