Turgut, NildaGuldiken, SibelBalci, KemalTugrul, ArmaganBerberoglu, UfukAltun, Betul Ugur2024-06-122024-06-1220060020-74541563-5279https://doi.org/10.1080/00207450600675340https://hdl.handle.net/20.500.14551/18903This article evaluates diagnostic sensitivity of minimal F-wave latency, sural/radial amplitude ratio ( SRAR), dorsal sural/radial amplitude ratio ( DSRAR), sympathetic skin response ( SSR), and R-R interval variability ( RRIV) for detecting early polyneuropathy in patients with glucose intolerance and diabetic patients. F-wave latencies were more prolonged in diabetic patients with normal and abnormal nerve conduction studies than control subjects ( p < .001). SRAR was lower, SSR latency was more prolonged, and RRIV was lower in diabetic patients with abnormal nerve conduction studies than healty controls ( p < .001). SSR latency was more prolonged and RRIV was lower in diabetic patients with normal nerve conduction studies than healty controls ( p < .01, p < .05, respectively). DSRAR was lower in diabetic patients with normal and abnormal nerve conduction studies than control subjects ( p < .001). DSRAR was also lower in patients with glucose intolerance than control subjects ( p < .01). DSRAR was the most sensitive and specific test in either of diabetic patients with normal nerve conduction studies ( sensitivity 66%, specificity 90%) and diabetic patients with abnormal nerve conduction studies ( sensitivity 100%, specificity 90%). DSRAR is the most reliable method for detection of early nerve pathology. Patients with glucose intolerance might have subclinical neuropathy that can be demonstrated with DSRAR analysis.en10.1080/00207450600675340info:eu-repo/semantics/closedAccessAutonomic NeuropathyDiabetes MellitusF-WaveGlucose IntolerancePolyneuropathySural NerveHeart-Rate VariationSympathetic Skin-ResponseSural Nerve-ConductionF-Wave LatencyAutonomic NeuropathyAutomatic-AnalysisClinical UtilityRate-VariabilityHealthyPrevalenceArticle1166745759Q4WOS:0002380212000062-s2.0-3374510300116753899Q2