Gökçe F.S.Coşkun İ.2024-06-122024-06-1220191309-9833https://doi.org/10.31362/patd.442558https://search.trdizin.gov.tr/yayin/detay/513911https://hdl.handle.net/20.500.14551/16589Purpose: Inguinal hernia is a prevalent condition among people of every sex, age and race and the treatment is surgery (1). One of the main goals during the surgery is to minimize surgical trauma. In this study, we aimed at finding out whether the intensity of surgical trauma and incision size differ between open inguinal hernia repair surgery and laparoscopic total extraperitoneal inguinal hernia repair surgery by measuring preoperative and postoperative levels of certain blood parameters that might reflect the intensity of trauma and response to trauma. Materials and Methods: A total of 40 patients who underwent inguinal hernia repair surgery were included in the study. 20 out of 40 patients underwent a laparoscopic total extraperitoneal inguinal hernia repair and 20 underwent open inguinal hernia repair. Blood samples were taken from the antecubital vein before the surgery, during the surgery, at hour 2 and hour 24 after the surgery and blood growth hormone, cortisol and malonyldialdehyde levels were measured. Results: No intergroup differences were found in age, sex and body mass index (p=0.78, p=0.429, p=0.616). Incision sizes were statistically smaller in laparoscopic technique (p<0.001). Elevated growth hormone levels were detected during the surgery by either technique. Growth hormone levels continued to increase at hour 2 in patients who underwent open surgery while a significant decrease was detected at hour 2 in patients who underwent laparoscopic surgery (p=0.005). Preoperative blood cortisol levels were found to be significantly elevated in both groups and significant reductions were detected at hour 2 after the surgery in patients who underwent laparoscopic repair (p=0.07) while significant reductions were detected in patients who underwent open repair at hour 24 after the surgery (p=0.006). No significant differences were detected among blood malonyldialdehyde concentrations measured before the surgery, during the surgery and at hour 2 and hour 24 after the surgery. However intergroup comparisons revealed that blood malonyldialdehyde concentrations were significantly higher in the open surgery group (p=0.038). Conclusion: Although laparoscopic surgery is not considered a gold standard for inguinal hernia repair, this approach may be the surgery of choice for inguinal hernia repair, particularly in cases of recurrent and bilateral inguinal hernia, as this technique is associated with lower levels of stress and trauma. © 2019, Pamukkale University. All rights reserved.tr10.31362/patd.442558info:eu-repo/semantics/openAccessGrafted Open Hernia Repair; Inguinal Hernia; Laparoscopic Hernia Repair; Stress HormonesArticle12155592-s2.0-85160905208N/A513911