Piri Cinar, BilgeKunt, RefikYuksel, BurcuGulluoglu, HalilSayilir, IdrisCeliker Uslu, SibelOzaydin Goksu, Eylem2024-06-122024-06-1220211368-50311742-1241https://doi.org/10.1111/ijcp.13955https://hdl.handle.net/20.500.14551/24812Aim of study: The NLR is a simple and inexpensive parameter that is useful as a marker of subclinical inflammation. The purpose of this study was to investigate the clinical characteristics of patients diagnosed with acute cerebral ischemia at the time of initial evaluation in the emergency department. Patients and methods: The study was designed as a multicentre cross-sectional study of acute ischemic stroke patients. Neurological evaluations were assessed using the NIHSS and mRS. Evaluations included the results of patients' laboratory tests performed at the time of presentation to the emergency department. Results: Seven hundred and thirty-five ischemic stroke patients were included in the study. Stroke cases assessed by the mRS as mild or severe showed significant differences with respect to age, leukocyte counts, neutrophil counts, NLR, LDL cholesterol values, and serum glucose values (P = .001). When analysed using NIHSS, lymphocyte levels were significantly higher in very severe stroke cases compared with mild, moderate, and severe cases. NLR was also significantly higher in very severe stroke cases and severe stroke cases as compared with the mild and moderate stroke groups. Neurological evaluations assessed using the mRS showed a mild positive correlation with neutrophil and leukocyte count and a weak correlation with the NLR. Conclusion: The NLR exhibited a significant correlation with the results of the mRS and NIHSS. The NLR measured in the very early period was also significantly associated with clinical condition. These results suggest that high NLR values may be a marker of stroke' severity.en10.1111/ijcp.13955info:eu-repo/semantics/openAccessBlood-Cell SubtypesNeutrophil/Lymphocyte RatioInflammatory ResponsesTerm MortalityPredictDiseaseCountsArticle754Q2WOS:0006068232000012-s2.0-8509923112933342005Q2