Aksit, ErcanGursul, ErdalAydin, FatihSamsa, MuratOzcelik, Fatih2024-06-122024-06-1220171995-18921680-0745https://doi.org/10.5830/CVJA-2016-045https://hdl.handle.net/20.500.14551/21704Aim: A person with a drop of more than 10% in nocturnal arterial blood pressure during the circadian rhythm is referred to as a dipper and one with a smaller decrease is referred to as a non-dipper. In our study, we aimed to compare the thrombolysis in myocardial infarction (TIMI) frame count in non-dipper and dipper hypertensive patient groups who had normal coronary artery angiography. Methods: Patients with normal coronary arteries and with ambulatory blood pressure monitoring follow ups were retrospectively investigated and 60 patients (35%, female) were included in our study. The patients were grouped as dipper (n = 30) and non-dipper (n = 30) hypertensives. Results: The TIMI frame counts in all three coronary arteries and the mean TIMI frame count in the dipper hypertensive patient group were significantly lower than those of the non-dipper hypertensives (right coronary artery TIMI frame count: 16.83 +/- 3.70; 21.63 +/- 3.44, p < 0.001; circumflex artery TIMI frame count: 21.28 +/- 3.52; 25.65 +/- 3.61, p < 0.001; left anterior descending artery TIMI frame count: 34.20 +/- 2.80; 37.05 +/- 3.30, p = 0.001; corrected left anterior descending artery TIMI frame count: 20.05 +/- 1.63; 21.74 +/- 1.95, p = 0.001; mean TIMI frame count: 19.31 +/- 2.3; 22.94 +/- 2.61, p < 0.001). The body mass index (BMI) was 23.79 +/- 2.81 kg/m(2) in the dipper patient group, while it was 25.47 +/- 2.92 in the non-dippers. BMI was found to be significantly higher in the non-dipper group than in the dipper group (p = 0.027). Conclusion: In this study, TIMI frame count, which is a simple, productive, objective and reproducible method for determination of microvascular changes, was found to be higher in non-dipper hypertensive patients than in the dipper patients.en10.5830/CVJA-2016-045info:eu-repo/semantics/openAccessHypertensionCoronary AngiographyTIMI Frame CountDipperNon-DipperTimi Frame CountDependent Vascular RelaxationBlood-Pressure VariationsAll-Cause MortalityCircadian VariationNitric-OxideArtery FlowUric-AcidThrombolysisDiseaseArticle2811418Q4WOS:0003972426000052-s2.0-8501535058927177043Q3