Tuna, FilizÖzdemir, HandeKabayel, Demirbağ DeryaDoğanlar, Zeynep Banu2024-06-122024-06-1220192149-3189https://doi.org/10.18621/eurj.411056https://search.trdizin.gov.tr/yayin/detay/405080https://hdl.handle.net/20.500.14551/12712Objectives: Individuals with joint hypermobility (JH) constitute a sensitive group with regard tomusculoskeletal problems. This study aimed to investigate whether females with generalized jointhypermobility (GJH) are at risk of hypovitaminosis D compared with non-GJH female participants and whetherthere is a relationship between vitamin D levels, Beighton score and musculoskeletal complaints.Methods: In this cross-sectional, descriptive and case-control study, 76 female participants aged 18-25 yearswere included. The Beighton score with a cut-off of 4/9 was applied for defining GJH. In addition, serumbiochemical (the enzymatic colorimetric method) and hormonal (the electrochemiluminescence method)parameters were evaluated.Results: The mean serum 25-hydroxyvitamin D (25[OH]D) levels of GJH (n = 38) and non-GJH (n = 38)groups were 15.70 ± 7.96 ng/mL and 16.80 ± 5.45 ng/mL, respectively. There was no statistically significantdifference between the groups in terms of biochemical and hormonal parameters. We found vitamin Ddeficiency in 89.5% of participants with GJH, and 84.2% of controls. There was no correlation between vitaminD, Brighton criteria, and musculoskeletal complaints.Conclusion: The female participants with GJH showed similar frequency of musculoskeletal complaints andsimilar low level of 25(OH)D in relation to controls.en10.18621/eurj.411056info:eu-repo/semantics/openAccessArticle54576581405080