Synthesis of platinum(II) complexes of 1-aryl-3-(benzimidazole-2-yl)- pyrazole-4-ketoximes and studies on their cytotoxic effects

Benkli K.Kayagil I.Incesu-Seller Z.Uluçam G.Demirayak Ş.2024-06-122024-06-1220081304-530Xhttps://hdl.handle.net/20.500.14551/17744In this research, synthesis of some complexes in the presence ofPt(II) were studied. The structure of the compounds were elucidated by IR, 1H-NMR, Mass and Elemental Analyses. The cytotoxicity of Pt-complex was evaluated. The cellular responses through MTT method were measured in normal rat embryo fibroblast line F2408 andH-ras active-rat embryo fibroblast line 5RP7.eninfo:eu-repo/semantics/closedAccessKetoximes; Metal Complexes; MttAntineoplastic Agent; Oxime Derivative; Platinum Complex; Animal Cell; Antineoplastic Activity; Article; Cell Viability; Controlled Study; Cytotoxicity; Drug Structure; Drug Synthesis; Embryo; Nonhuman; Physical Chemistry; Proton Nuclear Magnetic Resonance; RatSynthesis of platinum(II) complexes of 1-aryl-3-(benzimidazole-2-yl)- pyrazole-4-ketoximes and studies on their cytotoxic effectsArticle5145522-s2.0-68049087620Q3