Paksuz, Emine Pinar2024-06-122024-06-1220140065-12811618-0372https://doi.org/10.1016/j.acthis.2014.10.004https://hdl.handle.net/20.500.14551/19758Seasonal variations in morphometry and histochemistry of the intestine have been examined in the active and hibernating greater mouse-eared bat, Myotis myotis, using histological and histochemical techniques. The results of morphometric analyses indicated that hibernation affected the villus height, villus width, crypt depth and crypt width of the duodenum, jejunum and ileum. Histochemical analysis showed that goblet cells of the small and large intestine contain acidic and neutral mucosubstances. According to the results obtained with Alcian Blue (pH 5.8)/PAS staining, hyaluronic acid is dominant in the goblet cells of the small and large intestine during both the hibernation and active periods. Chondroitin sulfate and dermatan sulfate, which are sulfated GAGs, were dominant, and very little heparan sulfate, heparin and keratan sulfate were present. Moreover, sulfated glycoproteins were also detected in the goblet cells of the small intestine in the active animals. The present study demonstrates that hibernation altered the examined morphometric and histochemical parameters of the intestine. (C) 2014 Elsevier GmbH. All rights reserved.en10.1016/j.acthis.2014.10.004info:eu-repo/semantics/closedAccessChiropteraMyotis MyotisBatIntestineGlycosaminoglycansHibernationSmall-Bowel MucosaEpithelial-CellsSeasonal-ChangesDigestive-TractDietary FiberGastric MucusIn-VitroMucinStarvationRatArticle116814801489Q4WOS:0003473620000352-s2.0-8494016702625456312Q3