Turan, PinarTansel, OezlemEkuklu, GalipCelik, Ayguel Dogan2024-06-122024-06-1220081300-02922146-9040https://hdl.handle.net/20.500.14551/23788Objective: The objective of this study was to evaluate the epidemiological, clinical, laboratory features and risk factors associated with mortality of the 109 adult cases of sepsis in which gram positive, and gram negative bacteria isolated from blood cultures. Material and Methods: One hundred and nine patients with sepsis followed in our hospital between January 2002 and January 2003 were investigated prospectively. Results: Gram negative bacteria were isolated from blood cultures in the rate of 58.7%. The most frequent gram negative bacterium was Escherichia coli, and gram positive was Staphylococcus aureus. Statistically significant difference was not detected between gram positive, and gram negative bacteria sepsis related with development of hypothermia, appropriate antibiotic treatment, septic shock, multiple organ dysfunction syndrome (MODS), disseminated intravascular coagulation (DIC), and mortality rate. The mortality rate was 23%. The risk factors related with mortality were old age, hypothermia, staying in intensive care units, changes in consciousness, septic shock, MODS, DIC, renal failure, acute respiratory distress syndrome (ARDS), inappropriate antibiotherapy, and lack of infectious disease specialist consultation. Inappropriate antibiotic therapy, severe sepsis, and old age were found as independent factors in mortality by logistic regression analysis. Conclusion: There was no significant difference between the risk factors of gram positive, and gram negative bacteria sepsis. Prompt diagnosis and appropriate antibiotic treatment was important in decreasing the mortality in both of them.eninfo:eu-repo/semantics/closedAccessSepsisRisk FactorsFactors Influencing PrognosisBlood-Stream InfectionsNosocomial BacteremiaEpidemiologyMicrobiologyDefinitionsOrganismsTherapyImpactArticle286791797N/AWOS:0002623836000022-s2.0-60249085229Q4