Gubur, S.Ercan, A.Yazici, Z. M. Coskun2024-06-122024-06-1220220139-30061588-2535https://doi.org/10.1556/066.2022.00081https://hdl.handle.net/20.500.14551/19453This study was designed to investigate the effects of green tea on lipid profile, liver tissue damage, and oxidative stress in rats fed a diet including high fructose. Sprague-Dawley rats were randomly divided into four groups: Control (C), Fructose (F), Green Tea (GT), and F+GT. F and F+GT groups were given 20% fructose in the drinking water for eight weeks. Green tea (2 mg kg -1) was administrated to GT and F+GT groups by oral gavage for eight weeks. Biochemical parameters in serum and oxidative stress markers in the liver were analysed. The liver sections were stained with haematoxylin-eosin. As of the 3rd week of the experiment, the body weight of rats in the F group showed a statistically significant increase in comparison with the F+GT group. The serum glucose and triglyceride levels of the F+GT group significantly decreased when compared with the F group. The fructose-induced degenerative changes in the liver were reduced with green tea. Green tea may serve a protective role against hyperlipidaemia and liver injury in rats fed a high fructose diet.en10.1556/066.2022.00081info:eu-repo/semantics/openAccessCamellia SinensisFructoseGreen TeaLiverOxidative StressMetabolic DiseasesLipid-PeroxidationOxidative StressTriglyceridesCholesterolExpressionPlasmaArticle513437447Q4WOS:0009049380000122-s2.0-85137997057Q3