Pamuk, ÖNÇakir, NSoy, MAktoz, MÇelik, YAkdemir, O2024-06-122024-06-1220030770-3198https://doi.org/10.1007/s10067-002-0662-5https://hdl.handle.net/20.500.14551/18536We report the case of 36-year-old woman who came to us with a history of recurrent miscarriages and who was later diagnosed as having primary antiphospholipid syndrome (PAPS) and chronic hepatitis C virus (HCV) infection. The patient was referred to us with generalised seizures; cranial MRI revealed multiple embolic infarcts in both frontal lobes and a focal cortical infarct in the left frontoparietal lobe. Her echocardiography showed mitral valve vegetation and insufficiency. The patient was put on oral anticoagulant therapy and during her 8-month follow-up period no thrombotic events occurred. We report this case because it was the first in which PAPS, valvular disease, a cerebral embolic event and HCV infection were coexistent in the same patient. We also review other cases in which there was valvular vegetation and a cerebral ischaemic event associated with PAPS.en10.1007/s10067-002-0662-5info:eu-repo/semantics/closedAccessAnticardiolipin Antibody (Acl)Antiphospholipid Syndrome (APS)Cerebral Embolic EventHepatitis C Virus (HCV) InfectionMitral Valve VegetationLibman-Sacks EndocarditisAnticardiolipin AntibodiesIschemic EventsAssociationPrevalenceThrombosisDiseaseArticle222136139Q4WOS:00018355180001212740679