Akcay, SevilayUlger, MahmutOnurdag, Fatma KaynakDundar, Yasemin2024-06-122024-06-1220181318-02071580-3155https://doi.org/10.17344/acsi.2018.4590https://hdl.handle.net/20.500.14551/23456In this study, new pyrido [3,4-d]pyridazine derivatives were synthesized and evaluated for their in vitro antibacterial, antifungal and antimycobacterial activities. Among the synthesized compounds, compound 10 (1-(4-benzylpiperazin-1-yl) pyrido [3,4-d]pyridazin-4(3H)-one) and compound 12 (1-(4-benzylpiperidin-1-yl)pyrido [3,4-d]pyridazin-4(3H)-one) were found to have the highest antimycobacterial activity. However, all compounds were found ineffective against tested Gram-positive, Gram-negative bacteria and fungus.en10.17344/acsi.2018.4590info:eu-repo/semantics/openAccessPyrido [3,4-D]Pyridazine DerivativesPyrido [3,4-D]Pyridazin-4(3H)-OnePyrido [3,4-D]Pyridazin-1(2H)-OneAntimycobacterial ActivityPyrazinamideArticle654932938Q4WOS:0004532402000172-s2.0-8506130658433562929Q3