Kurtulus, Yasemin BakirciogluBakircioglu, DilekTopraksever, Nukte2024-06-122024-06-1220220889-15751096-0481https://doi.org/10.1016/j.jfca.2022.104682https://hdl.handle.net/20.500.14551/24278A novel and environmentally friendly three-liquid-phase extraction (TLPE) approach was developed for simultaneous separation of copper (Cu), magnesium (Mg) and zinc (Zn) from water samples. The proposed organic/ two aqueous phase system consists of di(2-ethylhexyl)phosphoric acid (D2EHPA), Choline Chloride:urea (deep eutectic solvent (DES)), and salt (K2HPO4). The effects of various factors including amount of DES and K2HPO4, pH, D2EHPA concentration, phase-mixing time, and diluent on the preconcentration/separation of Cu, Mg and Zn were evaluated. The results showed that 96.6% of Zn was concentrated in the D2EHPA-rich top phase, whereas 97.8% of Cu and 98.1% of Mg were quantitatively extracted into the DES-rich middle phase and salt-rich bottom phase, respectively. Excellent recovery (>97%) of Cu, Mg and Zn was obtained by using 20% (v/v) D2EHPA in hexane, and 1.72 g DES and 3.12 g K2HPO4 in two lower aqueous phases at pH= 4. The limits of detection were 1.58, 1.55 and 2.37 mg/L for Cu, Mg and Zn, respectively. Relative standard deviations (RSDs) for 0.5 mg/L and 1.0 mg/L of Cu, Mg and Zn in water samples were < 6%. The accuracy of the procedure was confirmed by analyzing a certified reference material of water and tea (NIST SRM 1640a, GBW 07605). Under optimized conditions, excellent agreement was observed between the TLPE-flame atomic absorption spectrometry (FAAS) results and certified values using the student's t-test (P = 0.05). TLPE procedure was successfully applied for the determination of Cu, Mg and Zn in water samples.en10.1016/j.jfca.2022.104682info:eu-repo/semantics/closedAccessThree-Liquid-Phase Extraction (TLPE)Deep Eutectic Solvent (DES)One-Step Simultaneous SeparationCopperMagnesiumZincWater AnalysisFloating Organic DropAbsorption Spectrometric DeterminationLiquid-Liquid MicroextractionCloud Point ExtractionAqueous 2-Phase SystemTrace AmountsIonic LiquidCopperZincPreconcentrationArticle112Q2WOS:0008334898000202-s2.0-85131967556Q1