Yanarda? H.Pamuk Ö.N.2024-06-122024-06-1220031424-7860https://hdl.handle.net/20.500.14551/17607Patients and Methods: Ocular disease is relatively common in sarcoidosis and can be the initial clinical manifestation in some instances. In this study, we retrospectively evaluated the clinical and demographic features of 9 (1.74%) patients with lacrimal gland (LG) involvement out of 516 sarcoidosis patients who were followed up at our centre over the preceding 36-years. In addition, the characteristics of patients with LG involvement were compared to those of other cases with eye involvement and to other sarcoidosis patients. Results: In 5 subjects with LG involvement, the chest X-ray was normal. The number of stage 0 subjects among other sarcoidosis patients was significantly lower than among patients with LG involvement (p <0.001). In 2 of these cases, the diagnosis of sarcoidosis was reached by LG biopsy. The mean age of patients with LG involvement was significantly lower than that of other sarcoidosis patients (p <0.001). Also, sarcoidosis-related organ involvement - other than of the LG - was more frequent than in other sarcoidosis patients (p <0.001). Conclusions: It should be borne in mind that LG involvement might be the initial manifestation of sarcoidosis and the chest X-ray in these patients might be completely normal.eninfo:eu-repo/semantics/closedAccessLacrimal Gland; Ocular Involvement; Sarcoidosis; UveitisAdolescent; Adult; Article; Biopsy; Clinical Article; Computer Assisted Tomography; Disease Course; Eye Disease; Female; Follow Up; Granulomatous Inflammation; Human; Lacrimal Gland Disease; Male; Nuclear Magnetic Resonance Imaging; Retrospective Study; Sarcoidosis; Thorax Radiography; UveitisArticle13327-283883912-s2.0-004269151812947527Q2