Boz, MesutTetik, OvulAltun, Ozlen2024-06-122024-06-1220221857-55521857-5625https://doi.org/10.20450/mjcce.2022.2526https://hdl.handle.net/20.500.14551/21564In the current study, firstly, a new pyrrole-based ligand (3,4-(ethylenedimercaptodiacetoxy)-N-(benzyl)-diethyl-2,5-pyrroledicarboxylate (L) was synthesized in the presence of diethyl-N-benzyl-3,4-dihydroxy-1H-pyrrole-2,5-dicarboxylate and 2,2'-(ethane-1,2-diylbis(sulfanediyl))diacetylchloride. Then, the palladium(II) complex of the synthesized ligand was obtained, and its structural features were examined by spectral (HRMS, ESI-MS, UV-Visible, FTIR, H-1 NMR, C-13 NMR, XRD-POWDER, SEM, EDX) and thermogravimetric (TG-DTA) techniques. The spectral and thermal measurements of the ligand and its Pd(II) complex show that the ligand is coordinated to the Pd2+ ion. Antimicrobial activities of both the ligand and its palladium complex were examined. It was determined that whereas the ligand indicated modest antimicrobial activity against Staphylococcus aureus and Candida albicans at a concentration of 6.25 mu g/ml, the palladium complex was significantly effective against C. albicans at a concentration of 6.25 mu g/ml.en10.20450/mjcce.2022.2526info:eu-repo/semantics/openAccessHeterocyclic CompoundsPalladium(II)Spectral CharacterizationBiological ActivityPt(Ii) ComplexesPalladium(Ii)Platinum(Ii)NanoparticlesArticle412Q4WOS:0008924924000022-s2.0-85147782702Q4