Oguz, FSOcal, LDiler, ASOzkul, HAsicioglu, FKasapoglu, EBozkurt, G2024-06-122024-06-1220040278-02401875-8630https://doi.org/10.1155/2004/565270https://hdl.handle.net/20.500.14551/23981The frequency and the distribution of HLA-B27 subtypes in spondylarthropathy (SpA) patients and controls were investigated in a sample Turkish population. B27 subtyping was performed by PCR-SSP method in two groups: 49 unrelated HLA-B27 positive Turkish patients with the diagnosis of SpA according to the European Spondyloarthropathy Study Group Criteria, and 55 HLA-B27 positive healthy controls. The frequency of HLA-B*27 was 2.6% in the Turkish population, and B*2705 was the predominant allele among patients with SpA. The difference was mainly between male patients and male controls The proportion of B*2705 among B27-positive patients and controls was significantly different (P = 0.02). Our study supports other reports from different populations which showed that B*2705 and B*2702 were more frequent in Caucasian patients with SpA.en10.1155/2004/565270info:eu-repo/semantics/openAccessSpondyloarthropathyHLA-B27Hla-B27 PolymorphismSusceptibilityAntigenArticle206309312Q2WOS:0002274603000032-s2.0-1524435525815665390Q2