Inal, Mehmet TuranMemis, DilekDemir, Emin TuncUyar, Ahmet SenolArslan, IsmailBozkurtlu, Poyraz2024-06-122024-06-1220202602-2974https://doi.org/10.4274/tybd.galenos.2020.88598https://search.trdizin.gov.tr/yayin/detay/376456https://hdl.handle.net/20.500.14551/23500Delirium is an organic dysfunction including the brain's inflammatory response to injury, hormonal effects and changes in neurotransmission and neural network. Delirium is one of the major causes of weaning difficulty in intensive care unit (ICU) patients. In this case report, we tried to explain the successful weaning procedure in a patient using quetiapine after trying all treatment options due to delirium in the ICU. This report emphasizes that second-generation antipsychotics should be kept in mind in patients who cannot be disconnected from the mechanical ventilator due to delirium.en10.4274/tybd.galenos.2020.88598info:eu-repo/semantics/openAccessQuetiapineWeaningDeliriumMechanical VentilationAdult PatientsDouble-BlindDeliriumDurationArticle183164167N/AWOS:000569133200008376456