Cinar, YildirimKosku, Nilufer2024-06-122024-06-122011978-981-08-8715-52010-4618https://hdl.handle.net/20.500.14551/24191International Conference on Life Science and Technology (ICLST 2011) -- JAN 07-09, 2011 -- Mumbai, INDIAThe aim of the study was to investigating of the relationships between temperature, flexibility of leukocytes, and viscosity, flow rate, pressure, and coagulation of blood. Method: Healthy 37 cases were chosen with Simple Random Sampling Method. Heparinized bloods were collected and then leukocyte suspensions were separated with the clinical centrifuge. The viscosity and flexibility of the samples were measured at 25 degrees C, 37 degrees C, and 39 degrees C with capillary tube viscometer. Hemodynamical parameters were calculated using Poiseuille's equation. The Pillai's Trace test was used for the statistical evaluation. Results: When the temperature of blood decreased from 37 degrees C to 25 degrees C, the viscosity of blood increased from 11.70+/-0.4s to 15.10+/-0.6s as 29.05% (p<0.0001). With a temperature increase from 37 degrees C to 39 degrees C, the viscosity of blood decreased from 11.70+/-0.4s to 10.12+/-0.35s as 13.50% (p<0.0001). Discussion: The data and flow charts of the study show that increase of blood viscosity due to decreased temperature could be related with decreased intracranial pressure, decreased blood flow rate, stasis, vasodilatation, headache, increased local concentration of coagulation factors that facilitate amplification of coagulation and formation of thrombus. Results of the study could provide capacities for distinct diagnosis, selective therapies, and regulation of cerebral blood flow; prevention from stasis, thrombus formation and bleeding; explanations of anemia related intracranial hypertension and headache; and it constitute a new expanded scalar base within mathematical accuracy for future investigations.eninfo:eu-repo/semantics/closedAccessTemperatureBlood ViscosityHeadacheCoagulationLeukocyte FlexibilityBlood Flow RateHemodynamicsHematocritFlowHeadachePressureVelocityConference Object3120126N/AWOS:000392766300031