Evranos-Aksöz, BegümOnurdağ, Fatma KaynakAksöz, ErkanÖzgacar, Selda Özgen2024-06-122024-06-1220201300-76881308-6529https://doi.org/10.19113/sdufenbed.672554https://search.trdizin.gov.tr/yayin/detay/376625https://hdl.handle.net/20.500.14551/12734Aseriesofhydrazonederivativesweresynthesizedtoinvestigate antifungal,antimicrobialandantitubercularactivities.Theseactivitieswere investigatedagainst Escherichiacoli, Escherichiacoli isolate, Pseudomonas aeruginosa, Pseudomonas aeruginosaisolate (resistant to gentamicin), Staphylococcus aureus, Staphylococcus aureus isolate (MRSA), Enterococcusfaecalis, Enterococcusfaecalis isolate(VRE), Candidaalbicans, Candidakrusei andMycobacteriumtuberculosis. Among the synthesized compounds B23had the best activity against Candida albicanswith 16 ?g/mL MIC value and B24had the best activity against Staphylococcus aureus isolate (MRSA) with 16 ?g/mL MIC value. The most effective compound against Mycobacteriumtuberculosis is found to be E9 with 32 ?g/mL MIC value, achalcone derivative. However, all compounds were determined as ineffective against Escherichia coli and Escherichia coli isolate.en10.19113/sdufenbed.672554info:eu-repo/semantics/openAccessArticle241196200376625