Usta, UfukTastekin, EbruIsler, ErhanKutlu, Ali K.Puyan, Fulya Oz2024-06-122024-06-1220140379-5284https://hdl.handle.net/20.500.14551/25053Objectives: To collect data on all detectable histologic and immune alterations from the kidneys of 55 autopsy cases. Methods: This prospective study was carried out at the Department of Pathology, Medical Faculty, Trakya University, Edirne, Turkey. Fifty-five cases were subjected to the study among 248 autopsies that were performed in 2011 and 2012. All kidney samples were evaluated under a light microscope and fresh tissue samples were used for immunofluorescence microscopy. Immunohistochemically kappa (kappa) and lambda (lambda) antibodies were applied to the tissue sections. The glomerular, tubulo-interstitial, and vascular alterations, as well as immune depositions were noted. Results: The microscopic morphology was close to normal histology in only 23 cases, and 23 cases had glomerular alterations. Nineteen cases had at least one immune deposition. There was immunoglobulin A deposition in 13 cases, and 9 cases showed positivity for both. and. immunohistochemically, and there was no clonal positivity. Conclusion: The most striking outcome of our study is the high rate of immune depositions. There was also a significant number of glomerular and non-glomerular renal alterations.eninfo:eu-repo/semantics/closedAccessHepatitis-C VirusRenal-DiseasesIga NephropathyBiopsyGlomerulonephritisClassificationPopulationFrequencyRegistryRiskArticle351113311338Q4WOS:0003459111000042-s2.0-8491001456725399209Q3