ULUGOL, AKARADAG, HCDOKMECI, DALKHATIB, IDOKMECI, I2024-06-122024-06-1219950091-3057https://doi.org/10.1016/0091-3057(94)00366-Qhttps://hdl.handle.net/20.500.14551/22510The protective effect of moclobemide, a reversible and highly selective inhibitor of monoamine oxidase-A, against hypoxia-induced lethality was investigated in the present experiment. Moclobemide showed an apparent protective potency against hypoxia and significantly prolonged the latencies for convulsions and death in a dose-dependent manner. Hypothermia is known to protect animals from hypoxia. Moclobemide also decreased body temperature in mice; however, the hypothermic effect was unrelated to the antihypoxic effect. These results suggest that the protective effect of moclobemide in hypoxia is not due to a decrease in body temperature.en10.1016/0091-3057(94)00366-Qinfo:eu-repo/semantics/closedAccessMOCLOBEMIDEHYPOXIABODY TEMPERATUREOxidase Type-ABarbiturate ProtectionReversible InhibitorHypothermiaPharmacologyProfileDrugsArticle512-3245247N/AWOS:A1995RB491000122-s2.0-00290423347667335Q1