Altun, AUgur, BAkdemir, OAltun, GDÖztekin, EBirsin, AÖzbay, G2024-06-122024-06-1220010167-5273https://doi.org/10.1016/S0167-5273(00)00455-1https://hdl.handle.net/20.500.14551/24297We investigated the ventricular repolarization changes during thyrotropin-releasing hormone (TRH) test in 20 euthyroid healthy subjects. TSH elevation was observed in 14 subjects (age: 29 +/- 5 years). TSH increased at 20 min (baseline: 1.91 +/- 1.18 muU/ml vs. 20 min: 13.7 +/- 7.2 muU/ml, P < 0.0001) and slightly decreased at 40 min (baseline vs. 40 min: 11.6 6.7 muU/ml P < 0.0001). Many dispersions prolonged at 20 and 40 min (P < 0.05). At baseline, 20 and 40 min, positive linear correlations were observed between TSH levels and TTd and TTcd, These data shows: that ventricular repolarization and regional inhomogeneity of ventricular repolarization increase during the TRH test. Neural and receptor-mediated mechanisms on repolarization kinetics of myocardial cells may act on this effect. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.en10.1016/S0167-5273(00)00455-1info:eu-repo/semantics/closedAccessThyroid Stimulating HormoneQT DispersionThyrotropin-Releasing Hormone TestVentricular RepolarizationQt Interval DispersionTorsade-De-PointesHypothyroidismLetter772-3319322Q2WOS:0001673950000322-s2.0-003513730811393138Q1