Cukurova, SelcukPamuk, Omer NuriUnlu, ErcumentPamuk, Gulsum EmelCakir, Necati2024-06-122024-06-1220120172-81721437-160Xhttps://doi.org/10.1007/s00296-011-1900-4https://hdl.handle.net/20.500.14551/21406We evaluated the incidence of subclinical atherosclerosis and associated factors in our gouty arthritis patients. We included 55 gouty arthritis patients diagnosed at our center within the last 4 years. The control group included 41 patients with rheumatoid arthritis (RA) and 34 patients with asymptomatic hyperuricemia (AHU). Atherosclerotic risk factors were determined in all subjects. Carotid intima-media thickness (IMT) and the presence of plaques were evaluated by B-mode ultrasonography. The carotid IMT in gouty arthritis patients (0.730 +/- 0.19) was significantly higher than in AHU subjects (0.616 +/- 0.12) (P = 0.004) and tended to be higher than the RA group (0.669 +/- 0.17) (P = 0.1). Atheromatous plaques were significantly more frequent in gouty arthritis patients (16 cases, 29.1%) than in RA patients (5 cases, 12.2%) and AHU subjects (3 cases, 8.8%) (P values, 0.05 and 0.023). Gout patients with plaques were older (P = 0.006) and tended to have tophi more frequently (P = 0.06). Logistic regression analysis showed that age (OR: 1.3, 95% CI: 1.02-1.54) and the presence of tophi (OR: 12.5, 95% CI: 1.2-140) were independent risk factors for the presence of plaques. Gouty arthritis bears a higher risk of atherosclerosis than both RA and AHU.en10.1007/s00296-011-1900-4info:eu-repo/semantics/closedAccessGouty ArthritisAtherosclerosisAsymptomatic HyperuricemiaRheumatoid ArthritisSystemic-Lupus-ErythematosusAcute Myocardial-InfarctionCoronary-Artery-DiseaseSerum Uric-AcidMetabolic SyndromeHeart-DiseaseCardiovascular-DiseaseRheumatoid-ArthritisEndothelial FunctionInflammationArticle32617691773Q3WOS:0003056803000432-s2.0-8486386402321442166Q2