Sarikaya, IsmetSchierz, Jan-HenningSarikaya, Ali2024-06-122024-06-1220212160-8407https://hdl.handle.net/20.500.14551/22175Liver has a complex and unique energy metabolism and plays a major role in glucose homeostasis. Liver is the main control center for glycogenesis, glycogenolysis, glycolysis and gluconeogenesis which are essential to provide energy for other tissues. Liver meets its own energy need from various sources which is mainly glucose in the fed state and fatty acids in the fasting state. In this review article, we will mainly describe the glucose metabolism of the liver, effect of various factors on 18F-fluorodeoxyglucose (FDG) activity/uptake in the normal liver and 18F-FDG positron emission tomography (PET) uptake patterns in various malignant and benign liver pathologies. Brief information on metabolomics profiling analyses in liver disorders will also be be provided.eninfo:eu-repo/semantics/closedAccessLiverGlucose MetabolismFDG PETLiver LesionsNodular Hyperplasia FnhHepatocellular-CarcinomaFdg-UptakeF-18-Fdg PetExtrahepatic MetastasesHepatic AngiosarcomaEnergy-MetabolismBlood-FlowIn-VivoCancerReview Article114233249N/AWOS:00070928790000134513277