Kaboglu, A2024-06-122024-06-1220040006-30881336-9563https://hdl.handle.net/20.500.14551/18203The process of aging has been investigated for a long time. Numerous theories were described to understand actual mechanism of aging. External environmental factors, genomic component, somatic mutation, harmful effects of free radicals, decline of the immune response and deficiency in the endocrine system, accumulation of glycosylation end products (AEGs), decreasing amount of heat-shock proteins (HSPs), telomeric shortening and calorie intake are thought to be related. Many questions exist about, the phenomenon aging and life span. This article represents a brief evaluation of aging theories and fundamental focus point of aging studies.eninfo:eu-repo/semantics/closedAccessAging TheoriesFree RadicalsTelomeric ShorteningCalorie IntakeDietary RestrictionLife-SpanCalorie RestrictionOxidative StressTelomeraseExtensionProteinAgeReceptorBrainReview Article593303308Q4WOS:0002228303000012-s2.0-3342972254Q3