Bedirhan B.Karamanlioglu B.Sengonul O.2024-06-122024-06-1219951016-5150https://hdl.handle.net/20.500.14551/17186This study was realized on 80 atherosclerotic and non-atherosclerotic patients to research effects of halothane and isoflurane on lipid metabolism. Patients were divided into two groups as halothane (H) and isoflurane (I). Each group consisted of 40 patients and also each group was divided into two subgroups as atherosclerotic (H1, I1) and non-atherosclerotic (H2, I2), equally. The plasma levels of cholesterol, HDL, LDL and triglyceride were investigated in venous blood samples that were taken before induction (stage I), at first (stage II), sixth (stage III), twenty-fourth (stage IV) and forty-eighth hours (stage V). The results were shown to us that, plasma levels of cholesterol, LDL were increased and HDL was decreased in group H1 and H2, significantly. In the group I1; level of cholesterol was increased, HDL was decreased but level of LDL didn't change. In the group I2; level of HDL showed significant decrease only at stage II. Triglyceride levels didn't show significant change in groups of H1, H2, I1, and I2. As a result of our study we can say that isoflurane is a better anaesthetic agent than halothane in atherosclerotic and non-atherosclerotic patients.trinfo:eu-repo/semantics/closedAccessAtherosclerosis Lipid; Cholesterol; Halothane; Hdl; Isoflurane; Ldl; TriglycerideCholesterol; Halothane; High Density Lipoprotein; Isoflurane; Low Density Lipoprotein; Triacylglycerol; Adult; Article; Atherosclerosis; Cholesterol Blood Level; Controlled Study; Female; Human; Lipid Metabolism; Major Clinical Study; MaleArticle23137412-s2.0-0028910377N/A