Kayabey, OzlemTuncer, TuncDeveci, MuratBasar, Evic ZeynepBabaoglu, Kadir2024-06-122024-06-1220212757-6256https://doi.org/10.5152/TurkArchPediatr.2020.20193https://search.trdizin.gov.tr/yayin/detay/446332https://hdl.handle.net/20.500.14551/22005Objective: This study aimed to determine the possibility of subclinical myocardial dysfunction detected by strain echocardiography in the late period of children with Kawasaki disease. Material and Methods: The study enrolled 30 patients with Kawasaki disease with a follow-up period of at least 12 months and 30 healthy age- and gender-matched children. During the follow-up period, standard echocardiography, pulsed and tissue Doppler, and strain echocardiography were recorded for both groups. Results: The mean age at the time of the diagnosis was 2.6 +/- 2.3 years (2 months-11 years). The mean follow-up period after the diagnosis was 3.55 +/- 2.20 years. Conventional echocardiography, M mode, pulsed and tissue Doppler values, and myocard performance index did not reveal significant differences. Left ventricle strain and strain rate parameters obtained by apical four-, three-, and two-chamber views did not show statistical differences between patients and controls. There was a positive correlation between the duration of follow-up and global fourand three-chamber longitudinal strain and global longitudinal strain values (r=0.465, p=0.010; r=0.414, p=0.023; r=0.492, p=0.006, respectively), whereas global radial strain showed negative correlation (r=-0.517, p=0.003). Conclusion: The analysis of systolic strain and strain rate did not detect a subclinical myocardial dysfunction in the long-term follow-up of Kawasaki disease. However, strain values showed variability with the follow-up periods, which indicates that Kawasaki disease might cause left ventricular dysfunction in the later phases. Therefore, a follow-up of children with a diagnosis of Kawasaki disease is of capital importance.en10.5152/TurkArchPediatr.2020.20193info:eu-repo/semantics/openAccessKawasaki DiseaseLeft Ventricular FunctionSpeckle Tracking ImagingStrainVentricular Systolic StrainConsequencesProfessionalsDeformationStatementHeartArticle5614450N/AWOS:0006216843000092-s2.0-8510075686334013229Q3446332