Guzel, AhmetKarasalihoglu, SerapAylanc, HakanTemizoz, OsmanHicdonmez, Tufan2024-06-122024-06-1220100735-6757https://doi.org/10.1016/j.ajem.2008.12.025https://hdl.handle.net/20.500.14551/25205Background: The aim of this study was to investigate the relationship between intracranial injury and serum tau protein levels in pediatric patients with minor head trauma (NI HT). Methods: We included 60 pediatric patients with MELT (Glasgow Coma Scale [GCS], 14-15) and 28 control patients. The patients were divided into 3 groups as follows: those without (group 1) and with (group 2) intracranial lesions shown on cranial computed tomography (CCT) and the control group (group 3). Results: The mean serum tau protein level was 96.06 +/- 70.36 pg/mL in group I. whereas it was 112.04 +/- 52.66 pg/mL in group 2, with no statistically significant difference between the groups (p = .160). The mean serum tau protein levels between the study groups (group I and group 2) and control (38.52 +/- 29.01) were statistically significant (P < .001 and P < .001, respectively). The GCS score and pathologic condition in CCT were only influential variables on tau protein levels. Conclusions: We found that serum tau protein increased after M HT but did not distinguish between those with and those without intracranial lesions demonstrable on CCT. (C) 2010 Elsevier Inc. All rights reserved.en10.1016/j.ajem.2008.12.025info:eu-repo/semantics/closedAccessNeuron-Specific EnolaseBrain-InjuryChildrenInterleukin-6SeverityS100bRuleArticle284399403Q2WOS:0002779848000022-s2.0-7795189270120466216Q1