Nadjat, TaıbTayeb, SıtayebBeşer, NecmiNadia, Aıssaouı2024-06-122024-06-1220212602-4772https://doi.org/10.29329/ijiaar.2021.378.2https://search.trdizin.gov.tr/yayin/detay/493521https://hdl.handle.net/20.500.14551/13100Novel coronavirus which was named later as SARS-CoV2 appeared in Wuhan, China, in the end of December 2019. Actually, no precise drugs are existed and research concerning SARS-CoV2 treatment is deficient. SARS-CoV2 main protease (Mpro) was crystallized by Liu et al. (2020) and represented a crucial drug target. The present work aimed to evaluate some bioactive compounds from Pistacia atlantica as possible SARS-CoV2 Mpro inhibitors, based on molecular docking approach. Molecular docking was carried out using AutoDock Vina software. The results indicated that Beta-Eudesmol, Elemol, Verbenol, Pinocarvone, Myrtenal, Myrtenol and Trans-Carveol have a potential inhibitor activity of SARS-CoV2 Mpro. Nevertheless, further investigations are required to develop and optimize drug process to combat SARS-CoV2.en10.29329/ijiaar.2021.378.2info:eu-repo/semantics/openAccessArticle53269278493521