EFFECTS OF CHROMOSOMAL TRANSLOCATIONS ON SPERM COUNT IN AZOOSPERMIC AND OLIGOSPERMIC CASES

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dc.authoridOzalp, Ozge Ozalp/0000-0002-7343-3064
dc.authoridYılmaz Gulec, Elif/0000-0003-0872-3898
dc.authoridSahin, Yavuz/0000-0002-7831-067X
dc.authoridYilmaz Gulec, Elif/0000-0003-0872-3898
dc.authoridYALCINTEPE, Sinem/0000-0002-8557-8885
dc.authorid, Akif/0000-0001-6930-7148
dc.authorwosidOzalp, Ozge Ozalp/ITT-5050-2023
dc.authorwosidYılmaz Gulec, Elif/GPS-8141-2022
dc.authorwosidSahin, Yavuz/E-9966-2013
dc.authorwosidGezdirici, Alper/W-8459-2018
dc.authorwosidOzalp Yuregir, Ozge/JCF-2622-2023
dc.authorwosidYilmaz Gulec, Elif/X-2778-2018
dc.contributor.authorAyaz, Akif
dc.contributor.authorYalcintepe, Sinem
dc.contributor.authorOzalp, Ozge
dc.contributor.authorGulec, Elif Yilmaz
dc.contributor.authorGezdirici, Alper
dc.contributor.authorAkcay, Ebru Perim
dc.contributor.authorKoseoglu, Abdullah Huseyin
dc.date.accessioned2024-06-12T10:54:08Z
dc.date.available2024-06-12T10:54:08Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: A number of mechanisms have been proposed for the effect of chromosomal translocations on spermatogenesis and sperm maturation. However, there are still numerous ambiguous issues regarding these two processes. The aim of this study is to evaluate the effect of chromosome break areas on sperm count in the light of the literature. Material and Methods: The study was conducted on the data of 16 male patients with reciprocal or Robertsonian translocation among 152 patients who were admitted to Adana Numune Training and Research Hospital and Kanuni Sultan Suleyman Training and Research Hospital Genetic Diagnosis Centers between 2013 and 2016 due to azoospermia and oligospermia. Results: 11 of these patients had reciprocal and five patients had Robertsonian translocations. All the patients with Robertsonian translocations were detected with azoospermia. Of the patients with reciprocal translocation, five of them were azoospermic and six of them were severe oligospermic. Conclusion: A total of 21 chromosomal breakpoints were identified in the 11 patients with reciprocal translocations. These chromosomal breakpoints may contribute to the clarification of ambiguous issues related to spermatogenesis and sperm maturation. The results also showed the importance of genetic counselling in patients with translocations.en_US
dc.identifier.doi10.30621/jbachs.1069678
dc.identifier.endpage927en_US
dc.identifier.issn2458-8938
dc.identifier.issn2564-7288
dc.identifier.issue3en_US
dc.identifier.startpage921en_US
dc.identifier.urihttps://doi.org/10.30621/jbachs.1069678
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18939
dc.identifier.volume6en_US
dc.identifier.wosWOS:000877003600027en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDokuz Eylul Univ Inst Health Sciencesen_US
dc.relation.ispartofJournal Of Basic And Clinical Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAzospermiaen_US
dc.subjectOligospermiaen_US
dc.subjectReciprocalen_US
dc.subjectRobertsonianen_US
dc.subjectSevere Oligozoospermiaen_US
dc.subjectSynaptonemal Complexen_US
dc.subjectMale-Infertilityen_US
dc.subjectMenen_US
dc.subjectInactivationen_US
dc.subjectAnomaliesen_US
dc.titleEFFECTS OF CHROMOSOMAL TRANSLOCATIONS ON SPERM COUNT IN AZOOSPERMIC AND OLIGOSPERMIC CASESen_US
dc.typeArticleen_US

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