Hormone replacement therapy process and effects of reproductive factors on bone mineral density in postmenopausal women

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dc.contributor.authorBalkanli-Kaplan, Petek
dc.contributor.authorOezden, Guelsah
dc.contributor.authorTokuc, Burcu
dc.contributor.authorYuece, M. Ali
dc.date.accessioned2024-06-12T10:54:55Z
dc.date.available2024-06-12T10:54:55Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives: The effects,of hormone replacement therapy (HRT) and reproductive factors such as parity, age of menopause, and duration of menopause on bone mineral density (BMD) in postmenopausal women were investigated. Patients and Methods: Age, reproductive history and HRT data of 322 postmenopausal women (mean age 52.4 +/- 6.2 years; range 3876) who applied to the outpatient menopause clinic of Trakya University Medical Faculty were gathered from the medical archives of the outpatient clinic. Patients were grouped according to the duration and current status of estrogen therapy and the effects of these variables on BMD were analysed. Bone mineral densities of lumbar spine, femur, trochanter, and Ward's triangle sites were measured by Dual Energy X-ray Absorptiometry (DEXA). Results: Bone mineral densities of trochanter, and Ward's triangle sites of postmenopausal women who received HRT for more than 3 years were found to be significantly higher than those women who were treated for less than 3 years. Vertebral bone densities were significantly higher in postmenopausal women who received HRT for more than 3 years, compared to those women who were never treated with HRT Ward's triangle and vertebral bone densities were significantly higher in postmenopausal Women who received HRT for more than 3 years and those currently on HRT, compared to those women who never received HRT BMD values of women who started but interrupted their HRTs, were similar to the values found in women who never received HRT Increasing parity and duration of menopause were the factors that reduced BMD values. Conclusion: It appeared that BMD of hip and spine increased in postmenopausal women after the third or more years on HRT and during the period of treatment with HRT. Parity and duration of menopause were identified as factors which increase the risk of osteoporosis.en_US
dc.identifier.endpage42en_US
dc.identifier.issn1301-3149
dc.identifier.issue1en_US
dc.identifier.startpage36en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19226
dc.identifier.volume24en_US
dc.identifier.wosWOS:000257598600008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherAves Yayincilik, Ibrahim Karaen_US
dc.relation.ispartofTrakya Universitesi Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Densityen_US
dc.subjectHormone Replacement Therapyen_US
dc.subjectMenopauseen_US
dc.subjectOsteoporotic Fracturesen_US
dc.subjectEstrogen-Treatmenten_US
dc.subjectHip Fractureen_US
dc.subjectOlder Womenen_US
dc.subjectPreventionen_US
dc.subjectMetaanalysisen_US
dc.subjectTrialen_US
dc.subjectRisken_US
dc.subjectMassen_US
dc.subjectSpineen_US
dc.titleHormone replacement therapy process and effects of reproductive factors on bone mineral density in postmenopausal womenen_US
dc.typeArticleen_US

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