Calcitonin related polypeptide alpha gene polymorphisms according to plasma total homocysteine levels in ischemic stroke patients of Trakya Region

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dc.authoridATILGAN, Emre/0000-0003-3759-7544
dc.authoridBakır, Alev/0000-0003-0664-5822
dc.authoridAlkanli, Nevra/0000-0002-3745-8838
dc.authorwosidBAKIR, Alev/AAZ-8403-2021
dc.authorwosidATILGAN, Emre/ACN-4163-2022
dc.authorwosidBakır, Alev/AAF-6907-2021
dc.authorwosidAlkanli, Nevra/D-4400-2019
dc.contributor.authorAlkanli, Nevra
dc.contributor.authorSipahi, Tammam
dc.contributor.authorAy, Arzu
dc.contributor.authorGuldiken, Baburhan
dc.contributor.authorBakir, Alev
dc.contributor.authorAlkanli, Suleyman Serdar
dc.contributor.authorCelebi, Canan
dc.date.accessioned2024-06-12T11:07:07Z
dc.date.available2024-06-12T11:07:07Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of this study was to determine the genotype distributions of calcitonin related polypeptide alpha (CALCA) gene polymorphisms according to the plasma total homocysteine levels in ischemic stroke patients and patient subtypes selected from Trakya Region. The study included 82 patients and 92 healthy controls. Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) were used to determine the genotype distributions of CALCA gene polymorphisms. The plasma total homocysteine levels were measured by Immulite 2000XPi homocysteine kits. Significant differences were not found between the group of patients and the control group in terms of CALCA gene polymorphisms genotype distributions (p > 0.05). Significant differences were not found between ischemic stroke patients and healthy controls, in the patient subtypes with ischemic stroke in respect to the CALCA gene polymorphisms genotype distributions according to the plasma total homocysteine levels (p > 0.05). This suggests that the CALCA gene polymorphisms genotype distributions studied according to the plasma total homocysteine levels could not likely be considered a genetic risk factor for ischemic stroke development.en_US
dc.description.sponsorshipScientific Research Projects Committee of Trakya University (TUBAP) [2013/13]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Committee of Trakya University (TUBAP) [grant number 2013/13].en_US
dc.identifier.doi10.1080/13102818.2017.1372218
dc.identifier.endpage1191en_US
dc.identifier.issn1310-2818
dc.identifier.issn1314-3530
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85029899245en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1184en_US
dc.identifier.urihttps://doi.org/10.1080/13102818.2017.1372218
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21898
dc.identifier.volume31en_US
dc.identifier.wosWOS:000414224000014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnology & Biotechnological Equipmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIschemic Strokeen_US
dc.subjectCALCA Gene Polymorphismsen_US
dc.subjectPCRen_US
dc.subjectRFLPen_US
dc.subjectPlasma Total Homocysteineen_US
dc.subjectPatient Subtypesen_US
dc.subjectRisken_US
dc.subjectAssociationen_US
dc.subjectHyperhomocysteinemiaen_US
dc.subjectHomocyst(E)Ineen_US
dc.subjectDiseaseen_US
dc.subjectCalcaen_US
dc.subjectC677ten_US
dc.titleCalcitonin related polypeptide alpha gene polymorphisms according to plasma total homocysteine levels in ischemic stroke patients of Trakya Regionen_US
dc.typeArticleen_US

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