The mitral valve prolapse frequency in healthy females with generalized joint hypermobility: A case-control study

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dc.authoridDemirbag Kabayel, Derya/0000-0003-1974-8054
dc.authoridTuna, Filiz/0000-0002-9563-8028
dc.authoridOzdemir, Hande/0000-0002-1717-9604
dc.authorwosidKABAYEL, Derya DEMIRBAG/AAB-3712-2021
dc.contributor.authorOzdemir, Hande
dc.contributor.authorTuna, Filiz
dc.contributor.authorAktoz, Meryem
dc.contributor.authorTastekin, Nurettin
dc.contributor.authorKabayel, Derya Demirbag
dc.date.accessioned2024-06-12T11:00:00Z
dc.date.available2024-06-12T11:00:00Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives: The aim of this study was to investigate the frequency of mitral valve prolapse between healthy females with generalized joint hypermobility and healthy controls. Patients and methods: This observational, cross-sectional, controlled study included female individuals with generalized joint hypermobility (n=39, mean age: 20.5 +/- 1.1 years; range, 19 to 23 years) and healthy controls (n=42, mean age: 20.6 +/- 1.2 years; range, 18 to 23 years) between July 2017 and November 2017. The generalized joint hypermobility consisted of women with a Beighton score of <= 4, while the control group consisted of women with a Beighton score of <= 3. Echocardiography was performed to all participants. Mitral valve prolapse was defined as having single or bileaflet prolapse of at least 2 mm beyond the long-axis annular plane with or without mitral leaflet thickening. Results: No significant difference was found in the age, height, body weight, and body mass index between the groups (p>0.05). The median Beighton score was 5 in the generalized joint hypermobility group and 2 in the control group. No mitral valve prolapse was detected in those with generalized joint hypermobility, while non-classical mitral valve prolapse was observed in one participant in the control group, indicating no statistically significant difference between the two groups (p> 0.05). Conclusion: Our study results suggest that the frequency of mitral valve prolapse is comparable between the women with generalized joint hypermobility and healthy controls. Based on these results, routine assessment of mitral valve prolapse is not recommended in this population.en_US
dc.description.sponsorshipScientific Research Committee of the Trakya University Scientific Research Projects Uniten_US
dc.description.sponsorshipThis research was supported by the Scientific Research Committee of the Trakya University Scientific Research Projects Unit.en_US
dc.identifier.doi10.46497/ArchRheumatol.2021.8192
dc.identifier.endpage340en_US
dc.identifier.issn2148-5046
dc.identifier.issn1309-0283
dc.identifier.issue3en_US
dc.identifier.pmid34870164en_US
dc.identifier.scopus2-s2.0-85107782767en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage335en_US
dc.identifier.trdizinid477001en_US
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2021.8192
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/477001
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20666
dc.identifier.volume36en_US
dc.identifier.wosWOS:000657515000003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives Of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEchocardiographyen_US
dc.subjectHeart Valve Diseaseen_US
dc.subjectJoint Laxityen_US
dc.subjectWomenen_US
dc.subjectMobilityen_US
dc.subjectFeaturesen_US
dc.subjectCollagenen_US
dc.subjectLinken_US
dc.titleThe mitral valve prolapse frequency in healthy females with generalized joint hypermobility: A case-control studyen_US
dc.typeArticleen_US

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