Immunotherapy in Elderly Cancer Patients

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dc.contributor.authorGokyer, Ali
dc.contributor.authorKucukarda, Ahmet
dc.contributor.authorCicin, Irfan
dc.date.accessioned2024-06-12T11:03:42Z
dc.date.available2024-06-12T11:03:42Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractTwo-thirds of all new cancer diagnoses are made in persons over the age of 65 years. It is unclear if age affects patient respons to immunotherapy, which is increasingly becoming first-line therapy in advanced stages of different tumor types. As a result of data obtained from different immunotherapy studies, it was seen that advanced age did not change safety and response. In these studies, it was found that drugs were generally in low toxicity profile and well tolerated in elderly and young patient subgroups. However, there are drug-specific differences for immune check-point inhibition in comparison of young patients and overall survival and progression-free survival rates in elderly individuals. Further studies should be conducted on patients who respond to and do not give medication to optimize the use of immunotherapy in elderly patients.en_US
dc.identifier.endpage109en_US
dc.identifier.isbn978-625-401-191-7
dc.identifier.startpage106en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21763
dc.identifier.wosWOS:000773800000018en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherOrtadogu Reklam Tanitim & Yayinciliken_US
dc.relation.ispartofTibbi Onkoloji - Geriatrik Onkolojien_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImmunotherapyen_US
dc.subjectCancer Survivorsen_US
dc.subjectDrug-Related Side Effects And Adverse Reactionsen_US
dc.subjectSquamous-Cell Carcinomaen_US
dc.subjectDouble-Blinden_US
dc.subjectIpilimumaben_US
dc.subjectPembrolizumaben_US
dc.subjectMulticenteren_US
dc.subjectMelanomaen_US
dc.subjectNivolumaben_US
dc.subjectRecurrenten_US
dc.subjectEfficacyen_US
dc.subjectPlaceboen_US
dc.titleImmunotherapy in Elderly Cancer Patientsen_US
dc.typeBook Chapteren_US

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