Inflammatory pseudotumor of the spleen with EBV positivity: report of a case
Küçük Resim Yok
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-Blackwell
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Inflammatory pseudotumor (IPT) of the spleen is a rare benign tumor with unknown etiology. It causes problems in the diagnosis because of mimicking some hematopoetic malignancies. Here we report the case of a 36-yr-old woman complaining of nausea and insomnia. Laboratory investigations were limited to increase of leukocyte and thrombocyte count. Ultrasonography and magnetic resonance (MR) imaging showed circumscribed solid lobulated mass, measuring about 6.5 cm in diameter, located in the dorsal region of the spleen. Splenectomy was performed with the differential diagnosis including hamartoma and lymphoma of the spleen. Histological examination of the sharply demarcated splenic mass consisted of myofibroblasts and admixture of inflammatory cells. Immunohistochemistry and in situ hybridization were performed. IPT of the spleen was diagnosed. Epstein-Barr virus (EBV) was detected in the tumor by in situ hybridization. This rare entity is presented because of its clinical, radiological and pathological difficulties in the differential diagnosis.
Açıklama
Anahtar Kelimeler
Inflammatory Pseudotumor, Spleen, Epstein-Barr Virus, Differential Diagnosis, Plasma-Cell Granuloma, Epstein-Barr-Virus, Myofibroblastic Tumor, Lymph-Nodes, Liver, Ultrasound, Entity, Child, Lung, Mri
Kaynak
European Journal Of Haematology
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
72
Sayı
4
