The value of magnetization transfer in delineation and differentiation of intracranial lesions

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dc.authorscopusid6603854521
dc.authorscopusid25723965900
dc.authorscopusid35564549100
dc.contributor.authorKarakas H.M.
dc.contributor.authorTasali N.
dc.contributor.authorCakir B.
dc.date.accessioned2024-06-12T10:25:11Z
dc.date.available2024-06-12T10:25:11Z
dc.date.issued2002
dc.description.abstractPurpose: Determination of the value of magnetization transfer (MT) imaging in the detection of lesions by evaluating the contrast difference between MT and non-MT spin-echo (SE) images of different types of enhancing intra-axial lesions, and the assessment of the applicability of MT effect (MTE) on lesion characterization. Methods: Twenty-seven patients (ages 11 to 72) having 36 lesion consisted of 12 multiple sclerosis plaques, nine metastatic lesions, 12 glial tumours and three abscesses were studied on 1.0 T imager with Gd-DTPA enhanced non-MT and MT sequences by application of 1500 Hz off-resonance pulse. Signal-to-noise ratios (SNR) and contrast-to-noise ratios (CNR) obtained with both techniques were compared to assess contrast improvement. MT effect (MTE) was used to evaluate the degree of saturation produced and its variances were analysed for lesion characterization. Results: The difference between MT and non-MT images for CNR was significant for all lesion types (P<0.05). Compared to the non-MTs, there was 60% improvement in CNR on MT images. MTE was not diagnostically significant in lesion characterization due to marked overlapping of MTE values for different lesion types. Conclusions: With the parameters used, MT almost doubles the CNR of enhancing intra-axial lesions, obviating the use of high dose regimens. © 2002 The College of Radiographers.en_US
dc.identifier.doi10.1053/radi.2001.0354
dc.identifier.endpage42en_US
dc.identifier.issn1078-8174
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-0036199772en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage35en_US
dc.identifier.urihttps://doi.org/10.1053/radi.2001.0354
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16228
dc.identifier.volume8en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherW.B. Saunders Ltden_US
dc.relation.ispartofRadiographyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectContrast Enhancement; Intracranial Lesions; Lesion Discrimination; Magnetic Resonance Imaging; Magnetization Transfer Contrasten_US
dc.subjectGadolinium Pentetate; Adolescent; Adult; Aged; Article; Brain Abscess; Brain Injury; Brain Metastasis; Clinical Article; Contrast Enhancement; Diagnostic Imaging; Diagnostic Value; Glioma; Human; Image Analysis; Multiple Sclerosis; Nuclear Magnetic Resonance Imaging; Priority Journal; School Child; Signal Noise Ratioen_US
dc.titleThe value of magnetization transfer in delineation and differentiation of intracranial lesionsen_US
dc.typeArticleen_US

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