Cardiopulmonary responses to exercise in moderate-to-severe obstructive sleep apnea.

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dc.authorscopusid35825964200
dc.authorscopusid55966023800
dc.authorscopusid6603402170
dc.authorscopusid23111808300
dc.authorscopusid6602617209
dc.contributor.authorOztürk L.M.
dc.contributor.authorMetin G.
dc.contributor.authorCuhadaroglu C.
dc.contributor.authorUtkusavaş A.
dc.contributor.authorTutluoglu B.
dc.date.accessioned2024-06-12T10:28:09Z
dc.date.available2024-06-12T10:28:09Z
dc.date.issued2005
dc.description.abstractInformation regarding the safety of maximal cardiopulmonary exercise testing (CPET) or the mechanisms of exercise limitation in obstructive sleep apnea (OSA) patients is fairly limited. In the present study, we addressed the problem of exercise capacity in moderate-to-severe OSA patients. Nineteen non-consecutive patients (three female, 16 male) with moderate-to-severe OSA and 11 age and body mass index matched control subjects (four female, seven male) underwent respiratory function tests during pre-exercise resting period and volitionally limited cardiopulmonary exercise testing on an electronically braked cycle ergometer. All participants completed CPET without any complication. Control subjects were exercise limited due to deconditioning. None of the patients revealed mechanical ventilatory limitation to exercise or had evidence of cardiac ischaemia. Five patients had no limitation to exercise. Six patients had low VO2peak, low anaerobic treshold (AT), and low peak O2 pulse, a pattern consistent with ventricular dysfunction. Six patients had low VO2peak, low AT, and peak heart rate less than 85% predicted. This pattern is consistent with exercise limitation due to peripheral vascular disease. Two patients had low VO2peak, low AT without peak oxygen pulse and peak heart rate abnormalities consistent with deconditioning. We concluded that moderate-to-severe OSA patients have impaired exercise capacity. Exercise limitation seems to originate from cardiovascular reasons namely left ventricular dysfunction and/or peripheral vascular impairment; and finally, maximal CPET can be tolerated by these patient group without serious complications.en_US
dc.identifier.endpage19en_US
dc.identifier.issn0494-1373
dc.identifier.issue1en_US
dc.identifier.pmid15765282en_US
dc.identifier.scopus2-s2.0-19844364943en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage10en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17106
dc.identifier.volume53en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTüberküloz ve toraksen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArticle; Evaluation; Exercise Tolerance; Female; Heart Rate; Hospitalization; Human; Lung Gas Exchange; Male; Middle Aged; Oxygen Consumption; Pathophysiology; Sleep Apnea Syndrome; Exercise Tolerance; Female; Heart Rate; Humans; Male; Middle Aged; Oxygen Consumption; Pulmonary Gas Exchange; Severity Of Illness Index; Sleep Apnea, Obstructiveen_US
dc.titleCardiopulmonary responses to exercise in moderate-to-severe obstructive sleep apnea.en_US
dc.typeArticleen_US

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