Value of Preoperative Indocyanine Green Clearance Test for Predicting Post-Hepatectomy Liver Failure in Noncirrhotic Patients

Basit Öğe Kaydı
dc.authoridSivrikoz, Nükhet/0000-0002-8299-3688
dc.authoridSahiner, Ibrahim Tayfun/0000-0002-3921-7675
dc.authoridgürtekin, başak/0000-0001-8806-2270
dc.authoridIbis, Cem/0000-0002-5602-375X
dc.authorwosidSivrikoz, Nükhet/HII-2942-2022
dc.authorwosidSoytaş, Yiğit/GWC-7416-2022
dc.authorwosidSahiner, Ibrahim Tayfun/B-4864-2015
dc.authorwosidgürtekin, başak/AAA-6231-2020
dc.authorwosidIbis, Cem/AAE-3388-2020
dc.contributor.authorIbis, Cem
dc.contributor.authorAlbayrak, Dogan
dc.contributor.authorSahiner, Tayfun
dc.contributor.authorSoytas, Yigit
dc.contributor.authorGurtekin, Basak
dc.contributor.authorSivrikoz, Nukhet
dc.date.accessioned2024-06-12T11:03:08Z
dc.date.available2024-06-12T11:03:08Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Liver failure is the most feared complication following hepatectomy. Post-hepatectomy liver failure (PHLF) is closely related to the remnant liver volume, and functional reserve. There are several methods for predicting PHLF prior to liver resection. The indocyanine green (ICG) clearance test was popularized in patients with hepatocellular cancer (HCC). We aim to demonstrate the value of preoperative ICG clearance measurement via pulse spectrophotometer (LIMON (R)) in prediction of PHLF in noncirrhotic patients prior to liver resection. Material/Methods: Fifty-three noncirrhotic patients who underwent liver resection due to different pathologies were included. Retrospectively collected clinical data, including the preoperative ICG clearance measurements and remnant liver volumes of the patients, were statistically evaluated according to the PHLF criteria of the International Study Group of Liver Surgery. Results: Four (7.5%) patients with PHLF were observed. There was no significant difference between PHLF and non-PHLF groups regarding ICG clearance measurements with cut-off values of 5% and 9.5%. Conclusions: The ICG clearance test does not satisfy our expectations in noncirrhotic patients in predicting PHLF. We believe that the ICG clearance test should be reserved for patients with cirrhosis and/or HCC. This test could be an option for noncirrhotic patients with chronic active hepatitis, advanced-grade fatty livers, or for patients who received long-term preoperative chemotherapy, and also for patients who underwent single or multiple sessions of TACE or TARE prior to liver resection. If the routine selection criteria have been fulfilled, there is no further need to perform the ICG clearance test for living liver donors.en_US
dc.identifier.doi10.12659/MSM.907306
dc.identifier.endpage4980en_US
dc.identifier.issn1643-3750
dc.identifier.pmid29042529en_US
dc.identifier.scopus2-s2.0-85032446431en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage4973en_US
dc.identifier.urihttps://doi.org/10.12659/MSM.907306
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21544
dc.identifier.volume23en_US
dc.identifier.wosWOS:000413190000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Scientific Literature, Incen_US
dc.relation.ispartofMedical Science Monitoren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatectomyen_US
dc.subjectIndocyanine Greenen_US
dc.subjectLiver Failurexen_US
dc.subjectHepatocellular-Carcinomaen_US
dc.subjectIsgls Definitionen_US
dc.subjectResectionen_US
dc.subjectValidationen_US
dc.subjectMortalityen_US
dc.subjectCirrhosisen_US
dc.subjectSurgeryen_US
dc.titleValue of Preoperative Indocyanine Green Clearance Test for Predicting Post-Hepatectomy Liver Failure in Noncirrhotic Patientsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu