Sağlıklı yetişkinlerde elma sirkesinin postprandiyal glisemi üzerine etkisi
Küçük Resim Yok
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Trakya Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Elma sirkesinin öğün sonrası 2 saatlik kan glukozuna etkisini araştıran bu çalışma, Mart 2021'de 36 katılımcı üzerinde gerçekleştirilmiştir. Tek kör, randomize, plasebo kontrollü gerçekleştirilen çalışma 18-50 yaş arası sağlıklı katılımcılar üzerinde yapılmıştır. Katılımcılar 8 saatlik gece açlığından sonra çalışmaya alınmışlardır. Çalışma başlangıcında kapiller kan glukoz değerleri ölçülmüş, 93 gram karbonhidrat içeren test öğünleri verilmiştir. Müdahale grubuna 300 mL [20 mL elma sirkesi (%5-6 asetik asit)] test içeceği verilmiş, kontrol grubuna ise 300 mL plasebo içecek verilmiş, verilen gıdaların 10 dakika içerisinde bitirilmesi istenmiştir. Başlangıçtan itibaren 30, 45, 60, ve 120. dakikalarda kapiller kan glukozu ölçülerek çalışma tamamlanmıştır. Çalışmada müdahale ve kontrol grubunun kan glukoz değerleri mg/dL cinsinden sırayla, 0. dk'da 84,67±5,92 ve 84,78±,29 (p=0,953), 30. dk'da 124,28±20,87 ve 134±17,78 (p=0,142), 45. dk'da 120,39±25,58 ve 130,5±22,40 (p=0,216), 60. dk'da 109,95±20,44 ve 123,83±19,92 (p=0,047), 120. dk'da 100,22±12,27 ve 103±19,28 (p=0,610) bulunmuştur. Altmışıncı dakikada bulunan yaklaşık 14 mg/dL'lik fark istatistiki olarak önemlidir (p=0,047). Tekrarlı ölçümlerde ANOVA değerlendirmesiyle 2 saatlik çalışma süresince istatistiki olarak önemli bir fark bulunamamıştır (p=0,288). İki grup arasında eğri altında kalan alan değerlendirmesiyle ölçüm alanları müdahale ve kontrol grubunda sırasıyla 153±26,59 dk*mg/dL ve 186,2±28,28 dk*mg/dL bulunmuştur, fark istatistiksel olarak anlamlıdır (p<0,001). Bulunan sonuç doğrultusunda çalışmadaki öğüne ek olarak verilen 20 mL elma sirkesinin postprandiyal glisemi üzerine düşürücü bir etkisi var görünmektedir. Bu çalışma elma sirkesinin akut bir etkisini araştırmıştır ve bilgimiz dahilinde ülkemizdeki ilk çalışmadır. Uzun süreli sirke kullanımının yan etkileri olabileceği çeşitli çalışmalarda gösterilmiştir. Gelecek çalışmalar sirke tüketiminin yarar ve risklerini ele almalı, tüm veriler ışığında yeni öneriler verilmelidir. Anahtar kelimeler: sirke, asetik asit, kan glukozu
EFFECT OF APPLE VINEGAR ON POSTPRANDIAL GLYCEMIA IN HEALTHY ADULTS SUMMARY The study, which was investigate the effect of apple cider vinegar on the 2-hour post-meal blood glucose, was carried out on 36 participants in March 2021. A single-blind, randomized, placebo-controlled study was conducted on healthy participants aged 18-50 years. Participants were recruited after an 8-hour night fast. At the beginning of the study, capillary blood glucose values were measured and test meals containing 93 grams of carbohydrates were given. The intervention group was given 300 mL [20 mL of apple cider vinegar (5-6% acetic acid)] test drink, while the control group was given 300 mL of placebo drink, and they were asked to finish the given food within 10 minutes. The study was completed by measuring capillary blood glucose at 30, 45, 60, and 120 minutes from the beginning. In the study, the blood glucose values of the intervention and control groups were 84.67±5.92 and 84.78±.29 at 0 min (p=0.953), 124.28±20 at 30 min, in mg/dL, respectively. 87 and 134±17.78 (p=0.142), 120.39±25.58 and 130.5±22.40 (p=0.216) at 45th min, 109.95±20 at 60th min, 44 and 123.83±19.92 (p=0.047), 100.22±12.27 and 103±19.28 (p=0.610) at 120 min. The difference of approximately 14 mg/dL at the 60th minute was statistically significant (p=0.047). No statistically significant difference was found during the 2-hour study period with the ANOVA in repeated measurements (p=0.288). With the evaluation of the area under the curve between the two groups, the measurement areas were found to be 153±26.59 min*mg/dL and 186.2±28.28 min*mg/dL in the intervention and control groups, respectively, the difference was statistically significant (p<0.001). In line with the results found, 20 mL of apple cider vinegar given in addition to the meal in the study seems to have a lowering effect on postprandial glycemia. This study investigated an acute effect of apple cider vinegar and, to the best of our knowledge, is the first study in our country. It has been shown in various studies that long-term use of vinegar can have side effects. Future studies should address the benefits and risks of vinegar consumption, and new recommendations should be given in the light of all data. Keywords: vinegar, acetic acid, blood glucose
EFFECT OF APPLE VINEGAR ON POSTPRANDIAL GLYCEMIA IN HEALTHY ADULTS SUMMARY The study, which was investigate the effect of apple cider vinegar on the 2-hour post-meal blood glucose, was carried out on 36 participants in March 2021. A single-blind, randomized, placebo-controlled study was conducted on healthy participants aged 18-50 years. Participants were recruited after an 8-hour night fast. At the beginning of the study, capillary blood glucose values were measured and test meals containing 93 grams of carbohydrates were given. The intervention group was given 300 mL [20 mL of apple cider vinegar (5-6% acetic acid)] test drink, while the control group was given 300 mL of placebo drink, and they were asked to finish the given food within 10 minutes. The study was completed by measuring capillary blood glucose at 30, 45, 60, and 120 minutes from the beginning. In the study, the blood glucose values of the intervention and control groups were 84.67±5.92 and 84.78±.29 at 0 min (p=0.953), 124.28±20 at 30 min, in mg/dL, respectively. 87 and 134±17.78 (p=0.142), 120.39±25.58 and 130.5±22.40 (p=0.216) at 45th min, 109.95±20 at 60th min, 44 and 123.83±19.92 (p=0.047), 100.22±12.27 and 103±19.28 (p=0.610) at 120 min. The difference of approximately 14 mg/dL at the 60th minute was statistically significant (p=0.047). No statistically significant difference was found during the 2-hour study period with the ANOVA in repeated measurements (p=0.288). With the evaluation of the area under the curve between the two groups, the measurement areas were found to be 153±26.59 min*mg/dL and 186.2±28.28 min*mg/dL in the intervention and control groups, respectively, the difference was statistically significant (p<0.001). In line with the results found, 20 mL of apple cider vinegar given in addition to the meal in the study seems to have a lowering effect on postprandial glycemia. This study investigated an acute effect of apple cider vinegar and, to the best of our knowledge, is the first study in our country. It has been shown in various studies that long-term use of vinegar can have side effects. Future studies should address the benefits and risks of vinegar consumption, and new recommendations should be given in the light of all data. Keywords: vinegar, acetic acid, blood glucose
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Yüksek Lisans
Anahtar Kelimeler
Beslenme ve Diyetetik, Nutrition and Dietetics
