Comparison of sufentanil and remifentanil during monitored anesthesia care
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Date
2003
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info:eu-repo/semantics/closedAccess
Abstract
In our study we aimed to compare remifentanil and sufentanil in monitored anesthesia care of septoplasty operations for consumption of propofol, analgesia, sedation and side effects. 50 patients scheduled for septoplasty operations were randomily divided into two groups of 25 patients in each received standardised premedication. Induction of sedation was done by 0.8 mg kg-1 propofol. Continoued by 2 mg kg-1 hr-1 and adjusted according to sedation scale. In Group 0.05 ?g kg-1 dk-1 remifentanil, in group II 0.25 ?g kg-1 hr-1 sufentanil infusion was started and adjusted according to scores of visuel rating scale. Intraoperative mean blood pressure, heart rate, SpO2 and visuel rating scale were evaluated and recorded at 5., 10., 20., 30., 40., and 50. mins. At the end of surgery study drugs were ended and total propofol, remifentanil, sufentanil consumptions were recorded. Alderete scores were evaluated 3 times at 15. min. interval after the termination of study drug. Intraoperative surgeon evaluation was done by 4 point scale. Postoperative 1., 2., 4., 6., 12. and 24. hrs mean blood pressure, heart rate, SpO2 and pain was evaluated by visual analog scale (VAS). When VAS scores were 4 or above 75 mg intramuscular diclophenac was given, first analgesic requirement time and total diclophenac consumptions were recorded. Total propofol consumptions were significantly high in group I when compared with group II (p<0.05). Aldrete scores in 15. min was lower in group II (p<0.05). Postoperative VAS values at 2. and 4. hrs were found to be higher in group I (p<0.05). First analgesic requirement time was significantly prolonged in group II (p<0.05), while there was on significant diffference in total diclophenac consumption. Respiratory depression and headache was encountered more in group I and difference was significant (p<0.05). Sufentanil infusion can be an alternative to remifentanil infusion in monitored anesthesia care.
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Keywords
Monitored Anesthesia Care; Remifentanil; Sufentanil, Diclofenac; Intravenous Anesthetic Agent; Nonsteroid Antiinflammatory Agent; Propofol; Remifentanil; Sufentanil; Adult; Agitation; Article; Blood Pressure; Clinical Article; Female; General Anesthesia; Headache; Heart Rate; Human; Intravenous Anesthesia; Male; Nose Septum Reconstruction; Oxygen Tension; Patient Monitoring; Postoperative Pain; Pruritus; Respiration Depression; Sedation; Visual Analog Scale
Journal or Series
Turk Anesteziyoloji ve Reanimasyon
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N/A
Volume
31
Issue
3
