A New Artificial Urine Protocol to Better Imitate Human Urine

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dc.authoridSARIGUL, NESLIHAN/0000-0002-5371-7924
dc.authoridkurultak, ilhan/0000-0001-5607-1375
dc.authoridKorkmaz, Filiz/0000-0003-3512-3521
dc.authorwosidSARIGUL, NESLIHAN/J-1564-2013
dc.authorwosidkurultak, ilhan/V-1616-2019
dc.authorwosidKorkmaz, Filiz/GOH-1457-2022
dc.contributor.authorSarigul, Neslihan
dc.contributor.authorKorkmaz, Filiz
dc.contributor.authorKurultak, Ilhan
dc.date.accessioned2024-06-12T11:20:06Z
dc.date.available2024-06-12T11:20:06Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractArtificial urine has many advantages over human urine for research and educational purposes. By closely mimicking healthy individuals' urine, it may also be important in discovering novel biomarkers. However, up until now, there has not been any specific protocol to prove the similarity in terms of the chemical composition at the molecular level. In this study, a new artificial urine protocol is established to mimics the urine of healthy individuals. The multi-purpose artificial urine (MP-AU) presented here is compared with two other protocols most cited in literature. Furthermore, these three protocols are also compared with samples from 28 healthy young individuals. To do so, attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) is used, according to which MP-AU shows a significantly close similarity with human urine. In formulating MP-AU, the infrared spectra of nine compounds is provided, making possible the band assignment of some absorption bands to certain compounds. Given its properties, the MP-AU protocol introduced here is both economical and practical, making it useful when designing comparative-controlled experiments.en_US
dc.identifier.doi10.1038/s41598-019-56693-4
dc.identifier.issn2045-2322
dc.identifier.pmid31882896en_US
dc.identifier.scopus2-s2.0-85077331106en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1038/s41598-019-56693-4
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25470
dc.identifier.volume9en_US
dc.identifier.wosWOS:000509340400038en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNature Portfolioen_US
dc.relation.ispartofScientific Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTransform Infrared-Spectroscopyen_US
dc.subjectSpot Urineen_US
dc.subject24-H Urineen_US
dc.subjectCreatinineen_US
dc.subjectCalciumen_US
dc.subjectProteinen_US
dc.subjectPopulationen_US
dc.subjectPotassiumen_US
dc.subjectMagnesiumen_US
dc.subjectDiagnosisen_US
dc.titleA New Artificial Urine Protocol to Better Imitate Human Urineen_US
dc.typeArticleen_US

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