Effect of extracorporeal shock wave lithotripsy on glomerular and tubular functions
Küçük Resim Yok
Tarih
1996
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kluwer Academic Publishers
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
To evaluate the early and late effects of extracorporeal shock wave lithotripsy on renal function, we prospectively designed a controlled study using a Direx lithotriptor. Twenty-five patients with renal stones and 16 healthy volunteers as the control group were included in the study. Blood und urine samples were collected before and after 24 hours, seven days and 8 months in the patient group. White blood cell count, serum levels of haemoglobin, urea, creatinine, SGOT, SGPT, AP, and LDH were determined. 24-hour urine specimens were collected to be tested for volume, excretion of creatinine, albumin, N-acetyl-?-glucosaminidase, ?-glutamyltransferase and ?-2-microglobulin. There were statistically significant increments in the secretion of urinary enzymes und albumin in the early period after ESWL, no longer lasting 8 months after the procedure. At 8 months one patient was hypertensive as judged by the diastolic pressure above 95 mm Hg. The results of this study showed that, although there was a transient glomerular und tubular damage after extracorporeal shock wave lithotripsy, the procedure seems safe und causes no permanent deterioration in renal function.
Açıklama
Anahtar Kelimeler
Adult; Article; Clinical Article; Clinical Trial; Controlled Clinical Trial; Controlled Study; Extracorporeal Lithotripsy; Female; Human; Kidney Function; Kidney Tubule Function; Male
Kaynak
International Urology and Nephrology
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
28
Sayı
3
