Initial presentation of an unspecified peripheral T-cell lymphoma as inflammatory polyarthritis and hypereosinophilia
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mattioli 1885 S.p.A.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Summary. Premise: There may be signs of joint and bone involvement in hematologic malignancies, but it is most rare for hematologic malignancies like lymphomas to present with joint symptoms. Patient: A 49-year-old male patient was admitted with rheumatoid arthritis-like symmetrical polyarthritis, morning stiffness, cutaneous vasculitis and hypereosinophilia. Autoantibodies, like rheumatoid factor, anti-citrullinated cyclic peptide, antinuclear antibody, anti-nuclear cytoplasmic antibody, were negative. After 4 months of follow-up, the patient developed a diffuse cutaneous rash and multiple lymphadenopathies. Lymph node biopsy was compatible with peripheral T-cell lymphoma, unspecified. Result: The patient was administered, respectively, CHOP and ICE chemotherapy regimens to which he was refractory. He died from infection and respiratory failure. Conclusion: It should be borne in mind that T-cell lymphomas may have unusual presentations with arthritis and hypereosinophilia. © Mattioli 1885.
Açıklama
Anahtar Kelimeler
Arthritis; Hypereosinophilia; Lymphoma; Peripheral T-Cell Lymphoma-Unspecified (Ptcl-U); Rheumatoid Arthritis (Ra), Carboplatin; Cd2 Antigen; Cd3 Antigen; Cd30 Antigen; Cd4 Antigen; Cd45ro Antigen; Cd7 Antigen; Cd8 Antigen; Cotrimoxazole; Cyclophosphamide; Diclofenac; Doxorubicin; Etoposide; Granulocyte Colony Stimulating Factor; Ifosfamide; Imipenem; Ki 67 Antigen; Methotrexate; Prednisolone; Vincristine; Adult; Arthralgia; Article; Bone Marrow Biopsy; Cancer Combination Chemotherapy; Case Report; Cervical Lymphadenopathy; Clinical Feature; Computer Assisted Tomography; Drug Substitution; Drug Withdrawal; Dyspnea; Eosinophil; Erythema; Erythrocyte Sedimentation Rate; Fever; Follow Up; Hepatosplenomegaly; Human; Human Tissue; Hypereosinophilia; Immunohistochemistry; Joint Swelling; Lymph Node Biopsy; Lymphadenopathy; Male; Middle Aged; Morning Stiffness; Multiple Cycle Treatment; Peripheral T Cell Lymphoma; Pneumonia; Polyarthritis; Rash; Rheumatoid Arthritis; Skin Biopsy; Splenomegaly; Vasculitis
Kaynak
European Journal of Oncology
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
21
Sayı
3
