Chitosan Effectiveness in End-to-End Vascular Anastomosis with Minimal Suture Technique

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dc.contributor.authorKandulu, Huseyin
dc.contributor.authorTop, Husamettin
dc.date.accessioned2024-06-12T11:08:32Z
dc.date.available2024-06-12T11:08:32Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground Vascular anastomosis, which is usually performed during complex surgical procedures such as transplantation and reconstruction, is a time-consuming and skilled practice. The aim of this study is to compare the vascular anastomosis technique made with minimal suture and chitosan with the traditional technique. Methods Twenty adult female Wistar Albino rats were randomly divided into two groups, the control group (n = 10) in which the traditional hand-sewn technique was applied and the chitosan group (n = 10) with the minimal suture technique. The duration of anastomosis, patency rates on the first and 28th days, and histopathology of the vessels on the 28th day were evaluated. Results The mean duration of anastomosis was calculated as 19.18 +/- 1.79 min in the control group and 11.30 +/- 0.97 min in the chitosan group. The difference between the two groups was statistically significant (p < 0.001). There was no significant difference between the patency rates of the control and chitosan groups, both within group (between the 1st and 28th days) and between the groups by day. In histopathological examination, especially in the control group, transmural damage, foreign body reactions due to the suture material, and granulomas were observed around the suture, while perivascular foreign body reactions were observed less frequently in the chitosan group compared to the control group. Conclusion We have shown that this new method of microvascular anastomosis is effective, easy to learn, and requires less time than conventional sutures. However, other studies should be conducted to prove the feasibility of this new technique and to prove its long-term success and results in the vessels.en_US
dc.identifier.doi10.1007/s12262-021-03177-3
dc.identifier.endpage264en_US
dc.identifier.issn0972-2068
dc.identifier.issn0973-9793
dc.identifier.issueSUPPL 1en_US
dc.identifier.scopus2-s2.0-85126373249en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage259en_US
dc.identifier.urihttps://doi.org/10.1007/s12262-021-03177-3
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22472
dc.identifier.volume85en_US
dc.identifier.wosWOS:000769843400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofIndian Journal Of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMicrovascular Anastomosisen_US
dc.subjectChitosanen_US
dc.subjectDuration Of Anastomosisen_US
dc.subjectPatency Rateen_US
dc.subjectRaten_US
dc.subjectMicrovascular Anastomosisen_US
dc.titleChitosan Effectiveness in End-to-End Vascular Anastomosis with Minimal Suture Techniqueen_US
dc.typeArticleen_US

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