Prevention of propofol injection pain in patients using transdermal nitroglycerine
Küçük Resim Yok
Tarih
2002
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Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In our study, we aimed to compare two different dosages of transdermal nitroglycerine with placebo in prevention of propofol injection pain. 150 patients from ASA II class who were to undergo various elective operations and who use transdermal nitroglycerine were assigned randomly in to three groups. In Gronp I pre-emptied transdermal nitroglycerine tape, in Group II transdermal nitroglycerine TTS 5 tape and in Group III transdermal nitroglycerine TTS 10 tape was applied 2 hours before the propofol injection, over the dorsum of the hand at the tip of intravenous cannula. After application of first 5 mL of propofol with a speed of 10 mg/5 sec, patients reaction and side effects were assessed. There was no propofol injection pain in 58% of group II patients and in 64% of group III patients, while different degrees of pain was seen in all the patients in placebo group. In 2% of group III patients and 10% of group II patients moderate to severe pain was seen, while moderate to severe pain was seen in 96% of patients in placebo group. There was no statistical difference between TNG- TTS 5 and TNG- TTS 10 dosages in reducing propofol pain, when compared with placebo significant difference was found. Propofol injection pain in patients using transdermal nitroglycerine used patients was significantly reduced when compared with placebo. Transdermal nitroglycerine can be useful in preventing propofol injection pain.
Açıklama
Anahtar Kelimeler
Propofol Injection Pain; Transdermal Nitroglycerin, Glyceryl Trinitrate; Placebo; Propofol; Article; Clinical Trial; Controlled Clinical Trial; Controlled Study; Dose Response; Drug Efficacy; Female; Human; Injection Pain; Major Clinical Study; Male; Pain Assessment; Randomized Controlled Trial; Side Effect; Statistical Analysis; Treatment Outcome
Kaynak
Turk Anesteziyoloji ve Reanimasyon
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
30
Sayı
4
