Comparative neurophysiological study for the diagnosis of mild polyneuropathy in patients with diabetes mellitus and glucose intolerance

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dc.contributor.authorTurgut, Nilda
dc.contributor.authorGuldiken, Sibel
dc.contributor.authorBalci, Kemal
dc.contributor.authorTugrul, Armagan
dc.contributor.authorBerberoglu, Ufuk
dc.contributor.authorAltun, Betul Ugur
dc.date.accessioned2024-06-12T10:54:05Z
dc.date.available2024-06-12T10:54:05Z
dc.date.issued2006
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThis article evaluates diagnostic sensitivity of minimal F-wave latency, sural/radial amplitude ratio ( SRAR), dorsal sural/radial amplitude ratio ( DSRAR), sympathetic skin response ( SSR), and R-R interval variability ( RRIV) for detecting early polyneuropathy in patients with glucose intolerance and diabetic patients. F-wave latencies were more prolonged in diabetic patients with normal and abnormal nerve conduction studies than control subjects ( p < .001). SRAR was lower, SSR latency was more prolonged, and RRIV was lower in diabetic patients with abnormal nerve conduction studies than healty controls ( p < .001). SSR latency was more prolonged and RRIV was lower in diabetic patients with normal nerve conduction studies than healty controls ( p < .01, p < .05, respectively). DSRAR was lower in diabetic patients with normal and abnormal nerve conduction studies than control subjects ( p < .001). DSRAR was also lower in patients with glucose intolerance than control subjects ( p < .01). DSRAR was the most sensitive and specific test in either of diabetic patients with normal nerve conduction studies ( sensitivity 66%, specificity 90%) and diabetic patients with abnormal nerve conduction studies ( sensitivity 100%, specificity 90%). DSRAR is the most reliable method for detection of early nerve pathology. Patients with glucose intolerance might have subclinical neuropathy that can be demonstrated with DSRAR analysis.en_US
dc.identifier.doi10.1080/00207450600675340
dc.identifier.endpage759en_US
dc.identifier.issn0020-7454
dc.identifier.issn1563-5279
dc.identifier.issue6en_US
dc.identifier.pmid16753899en_US
dc.identifier.scopus2-s2.0-33745103001en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage745en_US
dc.identifier.urihttps://doi.org/10.1080/00207450600675340
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18903
dc.identifier.volume116en_US
dc.identifier.wosWOS:000238021200006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal Of Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAutonomic Neuropathyen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectF-Waveen_US
dc.subjectGlucose Intoleranceen_US
dc.subjectPolyneuropathyen_US
dc.subjectSural Nerveen_US
dc.subjectHeart-Rate Variationen_US
dc.subjectSympathetic Skin-Responseen_US
dc.subjectSural Nerve-Conductionen_US
dc.subjectF-Wave Latencyen_US
dc.subjectAutonomic Neuropathyen_US
dc.subjectAutomatic-Analysisen_US
dc.subjectClinical Utilityen_US
dc.subjectRate-Variabilityen_US
dc.subjectHealthyen_US
dc.subjectPrevalenceen_US
dc.titleComparative neurophysiological study for the diagnosis of mild polyneuropathy in patients with diabetes mellitus and glucose intoleranceen_US
dc.typeArticleen_US

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